Can ICDs prevent sudden cardiac death effectively in patients with hypertrophic cardiomyopathy?

摘要

This observational, registry-based study included patients with a diagnosis of HCM who had undergone ICD implantation between 1986 and 2003 at 1 of 42 treatment centers in Australia, Europe, and the USA. Primary prevention of SCD via ICD implantation was indicated in HCM patients with any of the following risk factors: previous unexplained syncope of non-neurocardiogenic origin, massive left ventricular (LV) hypertrophy (maximum wall thickness >30mm), SCD in at least one first-degree relative aged younger than 50 years, and at least one episode of ventricular tachycardia confirmed by 24 h ambulatory Holter monitoring.