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Bioactive Secondary Metabolites Produced by the Fungal Endophytes of Conifers

机译:针叶树内生真菌产生的生物活性次生代谢产物

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摘要

This is a review of bioactive secondary metabolites isolated from conifer-associated endophytic fungi from 1990-2014, This includes compounds with antimicrobial, anti-inflammatory, anti-proliferative and cytotoxic activity towards human cancer cell lines, and activity against either plant pathogens or plant insect pests. Compounds that were originally reported without associated activity were included if other studies ascribed activity to these compounds. Compounds were not included if they were exclusively phytotoxic or if they were isolated from active extracts but were not determined to be the active component of that extract.
机译:这是对1990-2014年从针叶树相关的内生真菌中分离的具有生物活性的次级代谢产物的综述,其中包括对人癌细胞系具有抗微生物,抗炎,抗增殖和细胞毒性活性以及对植物病原体或植物有活性的化合物虫害。如果其他研究将活性归因于这些化合物,则包括最初报道的无相关活性的化合物。如果化合物仅具有植物毒性,或者如果它们是从活性提取物中分离出来的,但不能确定为该提取物中的活性成分,则不包括在内。

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