IBD: Antibodies to anti-TNF therapy-consequences for IBD management

摘要

As the authors claim, the clinical relevance of the study findings might be considerable, as a pancreatic fistula effects postoperative mortality and adds substantial hospital costs. Despite the length of hospital stay being reduced in patients who did not develop a pancreatic fistula (17 versus 27 days, the median length of stay of the overall study population (18 days) was rather long by the Western standard (8-10 days), probably because of institutional practices. The median length of stay did not differ substantially between the two trial arms, probably because the rate of postoperative morbidity (including nonsurgical site complications) was similar for the two groups. In particular, delayed gastric emptying without site-specific complications (for example, pancreatic fistula, biliary fistula or intraabdominal collection) was more common in patients who received a pancreatico-gastrostomy than in those who underwent pancreaticojejunostomy. Although delayed gastric emptying is not a life-threatening condition, it can be difficult to resolve and results in an extended hospital stay.