Gastrointestinal bledding: Novel nanopowder spray shows promising results in humans for the treatment of acute peptic ulcer bleeding.

摘要

The first human study of a novel nanopowder spray to achieve hemostasis was recently published, reporting promising results with an efficacy of 95% in patients with acute peptic ulcer bleeding."Current endoscopic therapies have their limits" says Joseph Sung, lead author. "They are skill-demanding, provide temporary hemostasis and are difficult to apply to bleeding lesions that cover a wide area." Animal studies of this novel nanopowder spray with clotting abilities have reported encouraging results and this led Sung and colleagues to conduct a proof-of-concept investigation to test its safety and efficacy in humans.Their prospective, single-arm, pilot study included 20 patients with confirmed active peptic ulcer bleeding.