The hippocampus is one of the principal sites of neurogenesis in the adult mammalian brain, but the contribution of adult-born neurons to hippocampal structure and hence normal brain function is unclear, as is the influence of an animal's environment on the generation of such cells. Now, Dranovsky eta!, show that in adult mice, hippocampat neural stem cells (NSCs) can give rise to persisting populations of neurons and stem cells, and that the ratio of stem cells to neurons can be affected by an animal's experiences.
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