PVA-chitosan composite hydrogel versus alginate beads as a potential mesenchymal stem cell carrier for the treatment of focal cartilage defects

Dashtdar Havva; Murali Malliga Raman; Abbas Azlina Amir; Suhaeb Abdulrazzaq Mahmod; Selvaratnam Lakshmi; Tay Liang Xin; Kamarul Tunku

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PVA-chitosan composite hydrogel versus alginate beads as a potential mesenchymal stem cell carrier for the treatment of focal cartilage defects

机译：PVA-壳聚糖复合水凝胶与藻酸盐微珠作为潜在的间充质干细胞载体，可用于治疗局部软骨缺损

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摘要

To investigate whether mesenchymal stem cells (MSCs) seeded in novel polyvinyl alcohol (PVA)-chitosan composite hydrogel can provide comparable or even further improve cartilage repair outcomes as compared to previously established alginate-transplanted models.

机译：与以前建立的藻酸盐移植模型相比，要研究接种在新型聚乙烯醇（PVA）-壳聚糖复合水凝胶中的间充质干细胞（MSC）是否可以提供相当或什至进一步改善软骨修复的效果。

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《Knee surgery, sports traumatology, arthroscopy: official journal of the ESSKA》 |2015年第5期|共10页
作者
Dashtdar Havva; Murali Malliga Raman; Abbas Azlina Amir; Suhaeb Abdulrazzaq Mahmod; Selvaratnam Lakshmi; Tay Liang Xin; Kamarul Tunku;
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正文语种 eng
中图分类外科学;
关键词
PVA-chitosan; Mesenchymal stem cell; Tissue engineering; Cartilage repair; Biomaterials;

机译：PVA-壳聚糖;间充质干细胞;组织工程;软骨修复;生物材料;

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1. PVA-chitosan composite hydrogel versus alginate beads as a potential mesenchymal stem cell carrier for the treatment of focal cartilage defects [J] . Dashtdar Havva, Murali Malliga Raman, Abbas Azlina Amir, Knee surgery, sports traumatology, arthroscopy: official journal of the ESSKA . 2015,第5期

机译：PVA-壳聚糖复合水凝胶与藻酸盐微珠作为潜在的间充质干细胞载体，可用于治疗局部软骨缺损
2. Fabrication and properties of an injectable sodium alginate/PRP composite hydrogel as a potential cell carrier for cartilage repair [J] . Gao Xiang, Gao Liyang, Groth Thomas, Journal of biomedical materials research, Part A . 2019,第9期

机译：用于软骨修复的潜在细胞载体的可注射钠藻酸钠/ PRP复合水凝胶的制造和性质
3. Mesenchymal Stem Cells Delivered in a Novel Cartilage Mimetic Hydrogel for the Treatment of Focal Chondral Lesions in an Equine Animal Model [J] . Cecilia Pascual-Garrido, Francisco Rodriguez-Fontan, Masahiko Haneda, Orthopaedic Journal of Sports Medicine . 2019,第7期

机译：新型软骨模拟水凝胶中的间充质干细胞在马动物模型中用于治疗局部软骨病变
4. Collagen Type Ⅰ and Ⅱ Blend Hydrogels with Mesenchymal Stem Cells as a Scaffold for Articular Cartilage Defect Repair [C] . Claire Kilmer, Abigail Durkes, Gert J. Breur, Society for Biomaterials annual meeting and exposition . 2019

机译：Ⅰ型和Ⅱ型胶原蛋白混合水凝胶与间充质干细胞作为支架修复关节软骨缺损
5. PEG-based hydrogels as chondrocyte carriers for tissue engineered cartilage: Controlling extracellular matrix evolution and integration with native cartilage. [D] . Rice, Mark Andrew. 2006

机译：基于PEG的水凝胶作为组织工程软骨的软骨细胞载体：控制细胞外基质的进化以及与天然软骨的整合。
6. Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect [O] . Hideyuki Koga, Masayuki Shimaya, Takeshi Muneta, 2008

机译：局部贴壁技术移植间充质干细胞作为软骨缺损的潜在治疗方法
7. Treatment outcomes of alginate-embedded allogenic mesenchymal stem cells versus autologous chondrocytes for the repair of focal articular cartilage defects in a rabbit model [O] . Tay L.X., Ahmad R.E., Dashtdar H., 2011

机译：藻酸盐包埋的同种异体间充质干细胞与自体软骨细胞在兔模型中修复局灶性软骨缺损的治疗结果

PVA-chitosan composite hydrogel versus alginate beads as a potential mesenchymal stem cell carrier for the treatment of focal cartilage defects

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