Cardiovascular Disease Knowledge Portal: A Community Resource for Cardiovascular Disease Research

摘要

Better understanding of the mechanisms underlying cardiovascular disease (CVD) is critical for improving prediction, diagnosis, and treatment of these conditions affecting millions of people worldwide.1 Large-scale genetic association studies have elucidated the genetic architecture of CVD biomarkers and outcomes; yet, translating these data into biological knowledge is challenging. To assist with this challenge, we developed the cardiovascular disease knowledge portal (CVDKP; broadcvdi. org) in collaboration with CVD researchers. The CVDKP is built on the Human Genetics Amplifier2 and is a component of the Common Metabolic Diseases Knowledge Portal (cmdkp.org) along with portals focused on cerebro-vascular disease,3 diabetes,2 and sleep disorders.