Plasma matrix metalloproteinase 1, 3, and 7 levels and breast cancer risk in the Nurses' Health Study

摘要

Matrix metalloproteinases (MMPs), in particular MMP1, 3, and 7, are believed to be critical to breast cancer invasion and metastasis and also may have important functions earlier in breast carcinogenesis. However, the relationship between circulating levels of MMP1, 3, and 7 and breast cancer risk is uncertain.