Mechanisms of clinical use of gestagens and their influence on canine and feline reproduction.

摘要

The aim of the paper was to determine the clinical uses of gestagens most commonly used in dogs and cats. Gestagens are widely used in the treatment of small animals with indications ranging from dermatological to behavioural problems. However, their main use involves the control of reproductive cycle which includes suppressing the ovarian cycle, suppressing abnormal sexual behaviour (especially in male dogs), and supplementing endogenous progesterone in pregnancies potentially compromised by insufficient luteal function. The article reviews the history, mechanisms, dosages, indications and contraindications of gestagens, as well as summarizing the gestational compounds used in veterinary medicine. It also discusses the clinical use of gestagens for the treatment of pseudopregnancy, nymphomania, pituitary dwarfism inhibition, short anoestrus, hypertrophy of prostate, male hypersexuality and spermatogenesis..