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首页> 外文期刊>Fitoterapia >Aqueous extract of Anemarrhena rhizome increases cell proliferation and neuropeptide Y expression in the hippocampal dentate gyrus on streptozotocin-induced diabetic rats.
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Aqueous extract of Anemarrhena rhizome increases cell proliferation and neuropeptide Y expression in the hippocampal dentate gyrus on streptozotocin-induced diabetic rats.

机译:知母根的水提物增加链脲佐菌素诱导的糖尿病大鼠海马齿状回中的细胞增殖和神经肽Y表达。

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摘要

In this study, the effects of the aqueous extract of Anemarrhena rhizome on cell proliferation and neuropeptide Y expression in the dentate gyrus of streptozotocin-induced diabetic rats were investigated via immunohistochemistry for 5-bromo-2'-deoxyuridine (BrdU) and neuropeptide Y. The results showed that the treatment with 50 to 200 mug/kg/day for 7 days of the aqueous extract of Anemarrhena rhizome increased new cell formation and neuropeptide Y expression in the dentate gyrus of diabetic rats reduced by the treatment with streptozotocin in rat.
机译:在这项研究中,通过免疫组织化学方法对5-溴2'-脱氧尿苷(BrdU)和神经肽Y进行了研究,研究了知母水提取物对链脲佐菌素诱导的糖尿病大鼠齿状回中细胞增殖和神经肽Y表达的影响。结果表明,用链脲佐菌素处理后,以50到200杯/千克/天的剂量处理连续7天的知母水提取物可增加糖尿病大鼠齿状回中新细胞的形成,并减少神经肽Y的表达。

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