The role of the peritoneal cavity in adhesion formation

摘要

The article by Barcz et al. (1) deserves a comment since it should make us think. Differences in peritoneal fluid constituents between women with and without endometriosis have been studied repetitively since the late 1970s in order to gain insight into the pathophysiology of endometriosis and associated infertility. Endometriosis is associated with a low-grade inflammation with more and more activated macrophages in peritoneal fluid. Despite the huge amount of data available, as this article also contributes to the data of cytokine concentrations, a comprehensive conclusion was never reached. More specifically, for most factors it remains speculative which are contributing to the development of endometriosis and which are a consequence of endometriosis (2).