Reply to the letter by Xing-Ru Zhang and Zhen-Yong Zhang: Comments on Inverse relationship between macular pigment optical density and axial length in Chinese subjects with myopia

摘要

We thank Xing-Ru Zhang and Zhen-Yong Zhang for their comments on our article [1]. In their letter, they discussed the relationship between macular pigment optical density (MPOD) and axial length (AL), and provided advice and suggestions regarding our findings. In our study, we used a limited sample size to investigate the relationship between AL and MPOD in myopic Chinese patients. We observed an inverse correlation between these two factors and a non-significant decrease in MPOD with increasing age. Although recent studies [2] on a larger sample group of the Chinese population noted a decrease of MPOD with increasing age, these findings were controversial. Raman et al [3] estimated the normal value of MPOD in an adult south Indian sample and found that the mean MPOD increased from 20-29 to 30-39 years.