CD40 ligand induces expression of vascular cell adhesion molecule 1 and E-selectin in orbital fibroblasts from patients with Graves' orbitopathy

Wang Hao; Zhu Li-Shuang; Cheng Jin-Wei; Cai Ji-Ping; Li You; Ma Xiao-Ye; Wei Rui-Li

首页> 外文期刊>Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie >CD40 ligand induces expression of vascular cell adhesion molecule 1 and E-selectin in orbital fibroblasts from patients with Graves' orbitopathy

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CD40 ligand induces expression of vascular cell adhesion molecule 1 and E-selectin in orbital fibroblasts from patients with Graves' orbitopathy

机译：CD40配体诱导Graves眼眶病患者眼眶成纤维细胞中血管细胞粘附分子1和E-选择素的表达

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摘要

The aim of this study was to detect the effect of the CD40 ligand (CD40L) on the expression of vascular cell adhesion molecule 1 (VCAM-1) and E-Selectin in orbital fibroblasts (OFs) from patients with Graves' orbitopathy (GO), as well as the signaling pathways involved in this effect.

机译：这项研究的目的是检测CD40配体（CD40L）对Graves眼眶病（GO）患者眼眶成纤维细胞（OFs）中血管细胞粘附分子1（VCAM-1）和E-选择素表达的影响以及与此效应有关的信号传导途径。

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《Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie》 |2015年第4期|共10页
作者
Wang Hao; Zhu Li-Shuang; Cheng Jin-Wei; Cai Ji-Ping; Li You; Ma Xiao-Ye; Wei Rui-Li;
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正文语种 eng
中图分类眼科学;
关键词
Graves' orbitopathy; CD40 ligand; Orbital fibroblast; Vascular cell adhesionmolecule 1; E-selectin;

机译：格雷夫斯眼病;CD40配体;眼眶成纤维细胞;血管细胞粘附分子1;E-选择素;

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专利

1. CD40 ligand induces expression of vascular cell adhesion molecule 1 and E-selectin in orbital fibroblasts from patients with Graves' orbitopathy [J] . Wang Hao, Zhu Li-Shuang, Cheng Jin-Wei, Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie . 2015,第4期

机译：CD40配体诱导Graves眼眶病患者眼眶成纤维细胞中血管细胞粘附分子1和E-选择素的表达
2. The expression of intercellular adhesion molecule-1 induced by CD40-CD40L ligand signaling in orbital fibroblasts in patients with Graves' ophthalmopathy. [J] . Zhao LQ, Wei RL, Cheng JW, Investigative ophthalmology & visual science . 2010,第9期

机译：格雷夫斯眼病患者眼眶成纤维细胞中CD40-CD40L配体信号诱导的细胞间粘附分子-1的表达
3. The Expression of Intercellular Adhesion Molecule-1 Induced by CD40-CD40L Ligand Signaling in Orbital Fibroblasts in Patients with Graves' Ophthalmopathy [J] . Li-Quan Zhao, Rui-Li Wei, Jin-Wei Cheng, Investigative ophthalmology & visual science . 2010,第9期

机译：格雷夫斯氏眼病患者眼眶成纤维细胞中CD40-CD40L配体信号诱导的细胞间黏附分子1的表达
4. Study the Role of E-selectin and Its Ligand sLeX in the Adhesion Between THP-1 Cells and HUVEC Cells [C] . Qian Zhang, Huan Liu, Chaoran Yao, International conference on applied biotechnology . 2018

机译：研究E-选择蛋白及其配体sLeX在THP-1细胞与HUVEC细胞之间的粘附中的作用
5. Epigenetic Basis for Heterogeneity in Vascular Cell Adhesion Molecule 1 Gene Expression in the Cytokine Activated Vascular Endothelium [D] . Turgeon, Paul Joseph. 2019

机译：细胞因子活化血管内皮中血管细胞粘附分子1基因表达的异质性的表观遗传学基础
6. Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin-4 selectively induces expression of vascular cell adhesion molecule-1 and P-selectin resulting in preferential adhesion of lymphocytes [O] . K Kotowicz, G L J Dixon, N J Klein, 2000

机译：CD40对人内皮细胞的生物学功能：与CD40配体和白介素4共同刺激选择性诱导血管细胞粘附分子1和P选择素的表达导致淋巴细胞优先粘附
7. Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin-4 selectively induces expression of vascular cell adhesion molecule-1 and P-selectin resulting in preferential adhesion of lymphocytes [O] . Kotowicz, K, Dixon, G L J, Klein, N J, 2000

机译：CD40对人内皮细胞的生物学功能：与CD40配体和白介素4共同刺激选择性诱导血管细胞粘附分子1和P选择素的表达，导致淋巴细胞优先粘附

CD40 ligand induces expression of vascular cell adhesion molecule 1 and E-selectin in orbital fibroblasts from patients with Graves' orbitopathy

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