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Deaths from drugs of abuse in Sheffield 1997-1999: what are the implications for GPs prescribing to heroin addicts?

机译:谢菲尔德1997-1999年因滥用毒品造成的死亡:开处方给海洛因成瘾者的全科医生有何影响?

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OBJECTIVE: Our aim was to examine the characteristics of drug abuse deaths in Sheffield between 1997 and 1999 with particular attention on the role of prescribed medication and the impact of increased methadone prescribing. METHODS: Information was made available on all deaths reported to the City of Sheffield Coroner between 1 January 1997 and 31 December 31 1999. These records were searched to identify individuals who died from a 'drug of abuse'-related poisoning. RESULTS: A total of 82 drug of abuse-related deaths occurred in Sheffield during the 3-year period. The number of deaths rose from 16 in 1997 to 34 in 1999 (112%), with the largest increase occurring between 1997 and 1998. The mean age over the period of study was 29.4 years (SD 7.5 years), the overwhelming majority of which were male (92%), single (89%) and unemployed (84%). Heroin on its own or in combination with other drugs was considered to be responsible for death in 70% of all cases. Deaths attributable either wholly or partially to methadone poisoning fell from 37% in 1997 to 18% in 1999. CONCLUSIONS: Given that the proportion of deaths involving methadone over this period fell against a background of increased prescribing, then it would appear that the availability of methadone is not a factor involved in the increase in the number of drug of abuse-related deaths in this study.
机译:目的:我们的目的是研究1997年至1999年谢菲尔德药物滥用死亡的特征,特别注意处方药的作用以及美沙酮处方增加的影响。方法:提供了有关1997年1月1日至1999年12月31日期间向谢菲尔德·科罗纳市报告的所有死亡的信息。对这些记录进行搜索,以识别死于“滥用毒品”相关中毒的人。结果:在三年期间,谢菲尔德共发生了82例与滥用相关的死亡药物。死亡人数从1997年的16人上升到1999年的34人(112%),最大的增加发生在1997年至1998年之间。研究期间的平均年龄为29.4岁(标准差为7.5岁),其中绝大多数分别为男性(92%),单身(89%)和失业(84%)。 70%的病例中,海洛因单独或与其他药物合用可导致死亡。全部或部分归因于美沙酮中毒的死亡人数从1997年的37%下降到1999年的18%。结论:鉴于在此期间处方涉及美沙酮的死亡人数下降的情况下,美沙酮中毒的可及性似乎有所增加。在这项研究中,美沙酮不是与滥用相关的死亡人数增加的因素。

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