Pharmacokinetic interaction between the CYP3A4 inhibitor ketoconazole and the hormone drospirenone in combination with ethinylestradiol or estradiol

Wiesinger Herbert; Berse Matthias; Klein Stefan; Gschwend Simone; Hchel Joachim; Zollmann Frank S.; Schuett Barbara

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Pharmacokinetic interaction between the CYP3A4 inhibitor ketoconazole and the hormone drospirenone in combination with ethinylestradiol or estradiol

机译：CYP3A4抑制剂酮康唑与激素屈螺酮与乙炔雌二醇或雌二醇合用时的药代动力学相互作用

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来源
《British Journal of Clinical Pharmacology》 |2015年第6期|共12页
作者
Wiesinger Herbert; Berse Matthias; Klein Stefan; Gschwend Simone; Hchel Joachim; Zollmann Frank S.; Schuett Barbara;
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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
contraception; cytochrome P-450 CYP3A4 inhibitors; drospirenone; drug interactions; ethinyl estradiol; hormone replacement therapy;

机译：避孕;细胞色素P-450 CYP3A4抑制剂;屈螺酮;药物相互作用;炔雌醇;激素替代疗法;

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1. Pharmacokinetic interaction between the CYP3A4 inhibitor ketoconazole and the hormone drospirenone in combination with ethinylestradiol or estradiol [J] . Wiesinger Herbert, Berse Matthias, Klein Stefan, British Journal of Clinical Pharmacology . 2015,第6期

机译：CYP3A4抑制剂酮康唑与激素屈螺酮与乙炔雌二醇或雌二醇合用时的药代动力学相互作用
2. Pharmacokinetic Evaluation of CYP3A4‐Mediated Drug‐Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults [J] . Townsend Robert, Dietz Albert, Hale Christine, Clinical pharmacology in drug development . 2017,第Suppla1期

机译：CYP3A4介导的异戊酰唑与利福平，酮康唑，咪达唑仑和乙炔雌二醇/ NORETHINDORON在健康成人中的药代动力学评价
3. Pharmacokinetic Evaluation of CYP3A4-Mediated Drug-Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults [J] . Robert Townsend, Albert Dietz, Christine Hale, Clinical pharmacology in drug development . 2017,第1期

机译：CYP3A4介导的异戊酰唑与利福平，酮康唑，咪达唑仑和乙炔雌二醇/ NORETHINDORON在健康成人中的药代动力学评价
4. Clinical Pharmacokinetics of the Novel Combination of BEZ235, PI3K/mTOR Inhibitor, and Everolimus, mTOR Inhibitor: Phase I Clinical Studies and Non-Clinical Mechanistic Assessment [D] . Moorthy, Ganesh P. 2015

机译：BEZ235，PI3K / mTOR抑制剂和依维莫司，mTOR抑制剂的新型组合的临床药代动力学：I期临床研究和非临床机制评估
5. Pharmacokinetic interaction between the CYP3A4 inhibitor ketoconazole and the hormone drospirenone in combination with ethinylestradiol or estradiol [O] . Herbert Wiesinger, Matthias Berse, Stefan Klein, 2015

机译：CYP3A4抑制剂酮康唑与激素屈螺酮与乙炔雌二醇或雌二醇合用时的药代动力学相互作用
6. Effects of CYP3A4 Inhibitors Ketoconazole and Verapamil and the CYP3A4 Inducer Rifampicin on the Pharmacokinetic Parameters of Fostamatinib: Results from In Vitro and Phase I Clinical Studies [O] . Paul Martin, Michael Gillen, David Millson, 2016

机译：CYP3A4抑制剂酮康唑和维拉帕米以及CYP3A4诱导剂利福平对Fostamatinib药代动力学参数的影响：体外和I期临床研究的结果

Pharmacokinetic interaction between the CYP3A4 inhibitor ketoconazole and the hormone drospirenone in combination with ethinylestradiol or estradiol

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