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Organ Printing from Stem Cells: Researchers Have Figured Out How to Use Modified Inkjet Technology to Print Cells

机译:从干细胞进行器官打印:研究人员已经弄清楚了如何使用改良的喷墨技术来打印细胞

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摘要

Tissue engineering is bringing together advances from stem cell biology, microfluid-ics, robotics, and 3-D cell culture to develop novel products for the drug development and toxicity testing sectors. The ability to create miniature tissue or even human organs-on-a-chip is valuable for a number of reasons. First, it has been shown that cells growing in more physiological 3-D cultures behave differently to the same cells when grown in the type of 2-D cultures currently being used in the drug development sector. Second, when analyzing the potential toxic effects that drug metabolites may have on other cell types, it would be useful to have an in vitro system that links the human liver to a chamber containing the test cell type.
机译:组织工程学将干细胞生物学,微流体技术,机器人技术和3-D细胞培养方面的先进技术融合在一起,以开发用于药物开发和毒性测试领域的新颖产品。出于多种原因,能够创建微型组织甚至单片人体器官的能力非常有价值。首先,已经表明,当在药物开发领域中使用的2-D培养类型中生长时,在更多生理3-D培养物中生长的细胞的行为与相同细胞不同。其次,在分析药物代谢物可能对其他细胞类型产生的潜在毒性作用时,拥有一种将人体肝脏与包含测试细胞类型的腔室相连的体外系统将非常有用。

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