DNA Topoisomerases I and II Inhibition and Cytotoxicity of Constituents from the Roots of Rubia cordifolia

摘要

The roots of Rubia cordifolia L.have been used in the Korean traditional medicine for the treatment of cough,the stone in the bladder and kidney,inflammation of the joints,uterine hemorrhage and uteritis.Several anthraquinones,anthraquinone glycosides,naphthoquinones,naphthoquinone glycosides,furomollugin,mollugin,alizarin,lucidin pimevero-side,ruberythric acid,purpurin,xanthopurpurin,cyclohexa-peptide,alkaloids and lignans from Rubia species have been reported.