Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney disease

Pitt Bertram; Anker Stefan D.; Boehm Michael; Gheorghiade Mihai; Kober Lars; Krum Henry; Maggioni Aldo P.; Ponikowski Piotr; Voors Adriaan A.; Zannad Faiez; Nowack Christina; Kim So-Young; Pieper Alexander; Kimmeskamp-Kirschbaum Nina; Filippatos Gerasimos

首页> 外文期刊>European journal of heart failure: journal of the Working Group on Heart Failure of the European Society of Cardiology >Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney disease

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Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney disease

机译：MinerA类激素受体拮抗剂耐受性研究-心力衰竭（ARTS-HF）的原理和设计：在患有糖尿病和/或慢性肾脏病的慢性心力衰竭加重的患者中，使用氟雷农和依普利农的随机研究

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AimsTo investigate the safety and potential efficacy of the novel non-steroidal mineralocorticoid receptor antagonist finerenone in patients with worsening chronic heart failure and reduced left ventricular ejection fraction (HFrEF) and at high risk of hyperkalaemia and worsening renal dysfunction.

机译：目的探讨新型非甾体类盐皮质激素受体拮抗剂氟雷酮在慢性心力衰竭加重，左心室射血分数（HFrEF）降低，高钾血症高危和肾功能不全高危患者中的安全性和潜在疗效。

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《European journal of heart failure: journal of the Working Group on Heart Failure of the European Society of Cardiology》 |2015年第2期|共9页
作者
Pitt Bertram; Anker Stefan D.; Boehm Michael; Gheorghiade Mihai; Kober Lars; Krum Henry; Maggioni Aldo P.; Ponikowski Piotr; Voors Adriaan A.; Zannad Faiez; Nowack Christina; Kim So-Young; Pieper Alexander; Kimmeskamp-Kirschbaum Nina; Filippatos Gerasimos;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Antagonist; Chronic kidney disease; Heart failure; Mineralocorticoid receptor; Type 2 diabetes mellitus;

机译：拮抗剂;慢性肾脏病;心力衰竭;盐皮质激素受体;2型糖尿病;

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1. Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney disease [J] . Pitt Bertram, Anker Stefan D., Boehm Michael, European journal of heart failure: journal of the Working Group on Heart Failure of the European Society of Cardiology . 2015,第2期

机译：MinerA类激素受体拮抗剂耐受性研究-心力衰竭（ARTS-HF）的原理和设计：在患有糖尿病和/或慢性肾脏病的慢性心力衰竭加重的患者中，使用氟雷农和依普利农的随机研究
2. A Randomized Controlled Study of Finerenone vs. Eplerenone in Japanese Patients With Worsening Chronic Heart Failure and Diabetes and/or Chronic Kidney Disease [J] . Naoki Sato, Masayoshi Ajioka, Takahisa Yamada, Circulation journal . 2016,第5期

机译：日本慢性心力衰竭加重和/或糖尿病和/或慢性肾脏病患者中呋内酯与依普利酮的随机对照研究
3. A randomized controlled study of finerenone vs. eplerenone in patients with worsening chronic heart failure and diabetes mellitus and/or chronic kidney disease [J] . Filippatos Gerasimos, Anker Stefan D., Boehm Michael, European Heart Journal: The Journal of the European Society of Cardiology . 2016,第27期

机译：慢性心力衰竭，糖尿病和/或慢性肾脏病加重患者中氟瑞农与依普利农的随机对照研究
4. Improvement of Haemodynamics by ATl-Antagonists-addition to ACE-inhibitor pretreated Patients with Severe Chronic Heart Failure Based on Coronary Artery Disease [C] . B. Gremmler, K. Kisters, M. Kunert, International Congress on Coronary Artery Disease . 2003

机译：基于冠状动脉疾病的ACE抑制剂预处理患者的ATL-拮抗剂改善血液肿瘤
5. The impact of telemonitoring on self -efficacy, emotional well -being, and clinical outcomes in patients with chronic obstructive pulmonary disease or heart failure [D] . West-Frasier, Jaclyn 2008

机译：远程监护对慢性阻塞性肺疾病或心力衰竭患者自我效能，情绪健康和临床结局的影响
6. A randomized controlled study of finerenone vs. eplerenone in patients with worsening chronic heart failure and diabetes mellitus and/or chronic kidney disease [O] . Gerasimos Filippatos, Stefan D. Anker, Michael Böhm, -1

机译：慢性心力衰竭糖尿病和/或慢性肾脏病加重患者中氟瑞农与依普利农的随机对照研究
7. Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study‐Heart Failure (ARTS‐HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney disease [O] . Pitt Bertram, Anker Stefan D., Böhm Michael, 2015

机译：矿物质类皮质激素受体拮抗剂耐受性研究的基本原理和设计 - 心力衰竭（aRTs-HF）：慢性心力衰竭伴糖尿病和/或慢性肾脏疾病恶化的患者的一项关于苯肾上腺素与依匹乐酮的随机研究

Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney disease

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