The association of traumatic brain injury with rate of progression of cognitive and functional impairment in a population-based cohort of Alzheimer's disease: the Cache County dementia progression study by Gilbert etal Late effects of traumatic brain injury on dementia progression

摘要

There is compelling evidence that traumatic brain injury (TBI) can trigger neurodegeneration, and that this is a major determinant of long-term outcome (Smith et al., 2013). A single significant injury such as a road traffic accident or exposure to a bomb blast can predispose an individual to Alzheimer's disease (AD), and here Gilbert and colleagues show for the first time that a history of TBI also alters the progression the disease.