Vitreous inflammatory factors and macular oedema.

摘要

INTRODUCTION Diabetic retinopathy (DR), branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO) are frequently complicated by macular oedema (MO), a condition that arises as a direct consequence of blood-retinal barrier (BRB) breakdown and the subsequent increase in vascular permeability. Accumulating evidence suggests that the upregulation of inflammatory factors or the downregulation of anti-inflammatory factors and a subsequent increase in leucocyte-endothelial interactions contribute to disruption of tight junctions and BRB breakdown.