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首页> 外文期刊>Indian medical journal >Study of the Efficacy and Safety of Liv. 52 DS Tablets in Alcoholic Hepatitis : Clinical, Biochemical and Ultrasonographic Evaluation
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Study of the Efficacy and Safety of Liv. 52 DS Tablets in Alcoholic Hepatitis : Clinical, Biochemical and Ultrasonographic Evaluation

机译:丽芙的功效和安全性研究。酒精性肝炎中52 DS片的临床,生化和超声检查评估

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摘要

Liver being the prime organ concerned with the metabolic and physiological homeostasis can undergo various pathological changes due to alcohol consumption. Acetaldehyde has long being suspected to be the causative agent for alcohol-induced liver damage. Xanthine oxidase may further add to this pathology due to superoxide generation. Aim : The present study was conducted on polyherbal, Liv.52 DS tablets to evaluate its efficacy in the treatment of alcohol-induced hepatitis. Material and Methods : This study was a phase III prospective randomized uncontrolled study undertaken in 25 patients of alcoholic hepatitis having duration of 8 weeks. Results and Conclusions : Clinical, biochemical, and Ultrasonographic evaluation has revealed beneficial effects of Liv.52 DS tablets in the management of alcoholic hepatitis. The drug was well tolerated.
机译:肝脏是与代谢和生理稳态有关的主要器官,会因饮酒而发生各种病理变化。长期以来,乙醛一直被认为是酒精引起的肝损伤的病因。黄嘌呤氧化酶可能会由于产生超氧化物而进一步加重这种病状。目的:本研究是针对52 DS的多草药片进行的,以评估其在治疗酒精性肝炎中的功效。材料和方法:本研究是一项针对25例持续8周的酒精性肝炎患者进行的III期前瞻性随机对照研究。结果与结论:临床,生化和超声检查评估显示Liv.52 DS片剂对酒精性肝炎的治疗具有有益作用。该药耐受性良好。

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