Antioxidant and nitric oxide synthase activation properties of Auricularia auricula

摘要

In vitro evaluation of antioxidant activities of Auricularia auricula showed significant inhibition of lipid peroxidation, and potent hydroxyl radical scavenging activity when compared with standard drug catechin. IC_(50) value of crude, boiled and ethanolic extracts of A. auricula represented 403, 510, and 373 mu g/ml respectively in case of hydroxyl radical scavenging activity and 310, 572 and 398 mu g/ml respectively in case of lipid peroxidation. Furthermore, crude, boiled and ethanolic extractsalso increase significantly nitric oxide production (664, 191 and 850 pmole/mg dry wt/hr respectively) over the control. The present results revealed that A. auricula had potential therapeutic use.