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首页> 外文期刊>Asian Journal of Organic Chemistry >A Catalyst-Free Approach to Construct 3-(Cyclopentenone)oxindoles Through a Phosphine-Ylide-Initiated Triple Domino Sequence
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A Catalyst-Free Approach to Construct 3-(Cyclopentenone)oxindoles Through a Phosphine-Ylide-Initiated Triple Domino Sequence

机译:一种无催化剂的方法通过膦-叶立德引发的三重多米诺骨牌序列构建3-(环戊烯酮)羟吲哚

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摘要

A catalyst-free domino reaction was developed for the synthesis of 3-(cyclopentenone)oxindoles. This method is the first example of a phosphine-ylide-initiated Wittig/Michael addition/Wittig domino sequence. The mild reaction conditions and broad functional groups tolerance make it highly valuable for synthesizing 3-(cyclopentenone)oxindoles.
机译:开发了无催化剂的多米诺反应,用于合成3-(环戊烯酮)羟吲哚。该方法是膦-内酯引发的Wittig / Michael加成/ Wittig多米诺骨牌序列的第一个示例。温和的反应条件和宽泛的官能团耐受性使其对于合成3-(环戊烯酮)羟吲哚具有很高的价值。

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