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Anticancer and Antimicrobial Studies on Mannich Bases of beta-Diketones

机译:β-二酮曼尼希碱的抗癌和抗菌研究

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摘要

Anticancer and antimicrobial activities of some 2-(N-aryl/hetero-arylaminomethyl)-1,3-diphenyl/1-phenyl-3-(3-nitrophenyl)/1-phe-nyl-3-(pyridin-3-yl)propan-1,3-diones were determined by adopting standard methods.Among the compounds tested the compounds IX and VI excel in their anticancer activity.In antibacterial screening,the same compounds showed more appreciable activity than the standard.In antifungal screening,all the compounds showed activity at 100mu/mL.
机译:某些2-(N-芳基/杂芳基氨基甲基)-1,3-二苯基/ 1-苯基-3-(3-硝基苯基)/ 1-苯甲基-3-(吡啶-3-基)的抗癌和抗菌活性用标准方法测定1,3-丙二酮的含量。在测试的化合物中,化合物IX和VI具有优异的抗癌活性。在抗菌筛选中,相同的化合物显示出比标准品更显着的活性。化合物在100μu/ mL时显示活性。

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