Silver-Catalyzed Alkyne Activation: The Surprising Ligand Effect

摘要

An unexpected ligand effect was discovered in the silver(I)-catalyzed alkyne activation. For both aldehyde-alkyne-amine (A~3) condensation and intermolecular alkyne hydroamination, the type B complex (P:Ag = 1:1) effectively promoted the reaction, while no reaction occurred with either no ligand or excess ligands under the identical conditions.