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首页> 外文期刊>American Journal of Sports Medicine >Operative versus Nonoperative Management of Acute Achilles Tendon Rupture: Expected-Value Decision Analysis.
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Operative versus Nonoperative Management of Acute Achilles Tendon Rupture: Expected-Value Decision Analysis.

机译:急性跟腱断裂的手术治疗与非手术治疗:期望值决策分析。

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摘要

BACKGROUND: The optimal management strategy for acute Achilles tendon rupture is controversial. PURPOSE: To determine the optimal management by using expected-value decision analysis. STUDY DESIGN: Cross-sectional study. METHODS: Outcome probabilities were determined from a systematic literature review, and patient-derived utility values were obtained from a visual analog scale questionnaire. A decision tree was constructed, and fold-back analysis was used to determine optimal treatment. Sensitivity analyses were used to determine the effect of varying outcome probabilities and utilities on decision-making. RESULTS: Outcome probabilities (expressed as operative; nonoperative) were as follows: well (0.762; 0.846), rerupture (0.022; 0.121), major complication (0.030; 0.025), moderate complication (0.075; 0.003), and mild complication (0.111; 0.005). Outcome utility values were well operative (7.9), well nonoperative (7.0), rerupture (2.6), major complication (1.0), moderate complication (3.5), and mild complication (4.7). Fold-back analysis revealed operative treatment as the optimal management strategy (6.89 versus 6.30). Threshold values were determined for the probability of a moderate complication from operative treatment (0.21) and the utility of rerupture (6.8). CONCLUSIONS: Operative management was the optimal strategy, given the outcome probabilities and patient utilities we studied. Nonoperative management was favored by increasing rates of operative complications; operative, by decreasing utility of rerupture. We advocate a model of doctor-patient shared decision-making in which both outcome probabilities and patient preferences are considered.
机译:背景:急性跟腱断裂的最佳治疗策略尚存争议。目的:通过使用期望值决策分析来确定最佳管理。研究设计:横断面研究。方法:从系统的文献综述中确定结果概率,并从视觉模拟量表中获得患者来源的效用值。构造决策树,并使用折返分析确定最佳治疗方案。敏感性分析用于确定不同结果概率和效用对决策的影响。结果:结果概率(表示为手术;非手术)如下:良好(0.762; 0.846),复发(0.022; 0.121),大并发症(0.030; 0.025),中度并发症(0.075; 0.003),轻度并发症(0.111) ; 0.005)。结果实用价值为手术良好(7.9),非手术良好(7.0),破裂(2.6),主要并发症(1.0),中度并发症(3.5)和轻度并发症(4.7)。折返分析显示手术治疗是最佳治疗策略(6.89 vs 6.30)。确定了因手术治疗引起的中度并发症的可能性的阈值(0.21)和复发的效用(6.8)。结论:鉴于我们研究的结局概率和患者效用,手术管理是最佳策略。非手术治疗因手术并发症发生率增加而受到青睐;手术,通过减少复发的效用。我们提倡一种医患共享决策模型,其中考虑了结果概率和患者偏好。

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