A randomized, multicenter, phase II study of vandetanib monotherapy versus vandetanib in combination with gemcitabine versus gemcitabine plus placebo in subjects with advanced biliary tract cancer: the VanGogh study

Santoro A.; Gebbia V.; Pressiani T.; Testa A.; Personeni N.; Bajardi E. Arrivas; Foa P.; Buonadonna A.; Bencardino K.; Barone C.; Ferrari D.; Zaniboni A.; Tronconi M. C.; Carteni G.; Milella M.; Comandone A.; Ferrari S.; Rimassa L.

首页> 外文期刊>Annals of oncology: official journal of the European Society for Medical Oncology >A randomized, multicenter, phase II study of vandetanib monotherapy versus vandetanib in combination with gemcitabine versus gemcitabine plus placebo in subjects with advanced biliary tract cancer: the VanGogh study

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A randomized, multicenter, phase II study of vandetanib monotherapy versus vandetanib in combination with gemcitabine versus gemcitabine plus placebo in subjects with advanced biliary tract cancer: the VanGogh study

机译：凡德他尼单药治疗与凡德他尼联合吉西他滨与吉西他滨联合安慰剂治疗晚期胆道癌的随机，多中心II期研究：VanGogh研究

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Background: The management of biliary tract cancers (BTCs) is complex due to limited data on the optimal therapeutic approach. This phase II multicenter study evaluated the efficacy and tolerability of vandetanib monotherapy compared with vandetanib plus gemcitabine or gemcitabine plus placebo in patients with advanced BTC.

机译：背景：由于关于最佳治疗方法的数据有限，胆道癌（BTC）的管理非常复杂。这项II期多中心研究评估了vandetanib单药疗法与vandetanib加吉西他滨或吉西他滨加安慰剂相比在晚期BTC患者中的疗效和耐受性。

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《Annals of oncology: official journal of the European Society for Medical Oncology》 |2015年第3期|共6页
作者
Santoro A.; Gebbia V.; Pressiani T.; Testa A.; Personeni N.; Bajardi E. Arrivas; Foa P.; Buonadonna A.; Bencardino K.; Barone C.; Ferrari D.; Zaniboni A.; Tronconi M. C.; Carteni G.; Milella M.; Comandone A.; Ferrari S.; Rimassa L.;
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正文语种 eng
中图分类肿瘤学;
关键词
vandetanib; gemcitabine; advanced biliary tract cancer;

机译：凡德他尼;吉西他滨;晚期胆道癌;

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2. A randomized, multicenter, phase II study of vandetanib monotherapy versus vandetanib in combination with gemcitabine versus gemcitabine plus placebo in subjects with advanced biliary tract cancer: the VanGogh study [J] . Santoro A., Gebbia V., Pressiani T., Annals of oncology: official journal of the European Society for Medical Oncology . 2015,第3期

机译：凡德他尼单药治疗与凡德他尼联合吉西他滨与吉西他滨联合安慰剂治疗晚期胆道癌的随机，多中心II期研究：VanGogh研究
3. A randomized phase II study of gemcitabine and S-1 combination therapy versus gemcitabine monotherapy for advanced biliary tract cancer. [J] . Takashi Sasaki, Hiroyuki Isayama, Yousuke Nakai, Cancer chemotherapy and pharmacology. . 2013,第4期

机译：吉西他滨的随机期II研究和S-1组合治疗对吉西他滨单药治疗晚期胆道癌。
4. Phase II randomized study of vandetanib plus gemcitabine or gemcitabine plus placebo as first-line treatment of advanced non-small-cell lung cancer in elderly patients [J] . GridelliC., NovelloS., ZilemboN., Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2014,第5期

机译：凡德他尼加吉西他滨或吉西他滨加安慰剂作为老年晚期晚期非小细胞肺癌的一线治疗的II期随机研究
5. Gemcitabine + Cisplatin Combination Electrochemotherapy for Triple Negative Breast Cancers: An in vitro Model Study [C] . R. Sundararajan, V. Raman, V. Masterson World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food Environmental Technologies . 2016

机译：Gemcitabine +顺铂组合电化学疗法三重阴性乳腺癌：体外模型研究
6. Predictive factors of the treatment outcome in patients with advanced biliary tract cancer receiving gemcitabine plus cisplatin as first-line chemotherapy [D] . 鈴木, 裕子 2019

机译：吉西他滨联合顺铂一线化疗对晚期胆道癌患者治疗效果的预测因素
7. Randomized Phase III study of gemcitabine plus S-1 versus gemcitabine plus cisplatin in advanced biliary tract cancer: Japan Clinical Oncology Group Study (JCOG1113 FUGA-BT) [O] . Junki Mizusawa, Chigusa Morizane, Takuji Okusaka, -1

机译：吉西他滨加S-1与吉西他滨加顺铂在晚期胆道癌中的随机III期研究：日本临床肿瘤学小组研究（JCOG1113FUGA-BT）
8. Phase II Randomized Study of Vandetanib Plus Gemcitabine or Gemcitabine Plus Placebo as First-Line Treatment of Advanced Non–Small-Cell Lung Cancer in Elderly Patients [O] . Gridelli Cesare, Novello Silvia, Zilembo Nicoletta, 2014

机译：Vandetanib加吉西他滨或吉西他滨加安慰剂作为老年晚期非小细胞肺癌一线治疗的II期随机研究

A randomized, multicenter, phase II study of vandetanib monotherapy versus vandetanib in combination with gemcitabine versus gemcitabine plus placebo in subjects with advanced biliary tract cancer: the VanGogh study

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