A microarray-based resonance light scattering assay for detecting thrombin generation in human plasma by gold nanoparticle probes

摘要

A peptide microarray-based resonance light scattering (RLS) assay with gold nanoparticle probes has been developed for monitoring thrombin generation in human plasma. Thrombophilia, hypo-coagulability and normal plasma have been successfully differentiated by the assay.