C-H Functionalization and Nucleophilic Aromatic Substitution of Electron-rich Arenes

摘要

Synthesis of multi-substituted arenes is one of the most important areas of research in organic synthesis. This review discusses new methodologies to introduce various nucleophiles to electron-rich arenes by photoredox catalysis. These methodologies can be considered as complementary to the traditional nucleophilic aromatic substitution, which uses electron-deficient arenes as substrates.