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Association of particulate air pollution with daily mortality: The China air pollution and health effects study

机译:微粒空气污染与每日死亡率的关联:中国空气污染与健康影响研究

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摘要

China is one of the few countries with some of the highest particulate matter levels in the world. However, only a small number of particulate matter health studies have been conducted in China. The study objective was to examine the association of particulate matter with an aerodynamic diameter of less than 10 μm (PM 10) with daily mortality in 16 Chinese cities between 1996 and 2008. Two-stage Bayesian hierarchical models were applied to obtain city-specific and national average estimates. Poisson regression models incorporating natural spline smoothing functions were used to adjust for long-term and seasonal trends of mortality, as well as other time-varying covariates. The averaged daily concentrations of PM 10 in the 16 Chinese cities ranged from 52 μg/m 3 to 156 μg/m 3. The 16-city combined analysis showed significant associations of PM 10 with mortality: A 10-μg/m 3 increase in 2-day moving-average PM 10 was associated with a 0.35% (95% posterior interval (PI): 0.18, 0.52) increase of total mortality, 0.44% (95% PI: 0.23, 0.64) increase of cardiovascular mortality, and 0.56% (95% PI: 0.31, 0.81) increase of respiratory mortality. Females, older people, and residents with low educational attainment appeared to be more vulnerable to PM 10 exposure. Conclusively, this largest epidemiologic study of particulate air pollution in China suggests that short-term exposure to PM 10 is associated with increased mortality risk.
机译:中国是世界上颗粒物含量最高的少数几个国家之一。但是,在中国仅进行了少量的颗粒物健康研究。该研究的目的是检验空气动力学直径小于10μm(PM 10)的颗粒物与1996年至2008年间中国16个城市的每日死亡率之间的关系。采用两阶段贝叶斯分级模型来获得特定于城市和全国平均估计。结合自然样条平滑功能的Poisson回归模型用于调整死亡率的长期和季节性趋势以及其他随时间变化的协变量。在中国16个城市中,PM 10的平均日浓度在52μg/ m 3至156μg/ m 3之间。16个城市的联合分析显示,PM 10与死亡率之间存在显着相关性:10μg/ m 3的增加。 2天移动平均PM 10与总死亡率增加0.35%(95%后路间隔(PI):0.18,0.52),0.44%(95%PI:0.23,0.64)与心血管疾病死亡率相关以及0.56 %(95%PI:0.31,0.81)增加呼吸道死亡率。女性,老年人和文化程度低的居民似乎更容易受到PM 10的影响。最终,这项针对中国微粒空气污染的最大规模的流行病学研究表明,短期暴露于PM 10会增加死亡风险。

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