Polythylene Glycol-Polyvinyl Alcohol Graft Copolymer:A Peroxide-Free Binder

摘要

Excipients are integral components of solid oral dosage formulations (SODF). Therapeutic efficacies of these dosages are dependent upon the excipients'function and method of use, and also their interactions with active ingredients (APIs). These excipients, commonly used as fillers, binders, disintegrants and/or coatings in tablets and pellets, contribute to the dosage's shape and size, delivery and stability. Formulation technologies are as important as excipient selection and both contribute to delivery and stability of APIs in the dosages. Therefore, the efforts continue to identify the appropriate excipients in the development of stable and efficacious SODFs amenable to desired formulation platforms or technologies accepted by the industry.