Synthesis of Some Novel Heteroannulated Pyrano[3,2‐ cc ]quinoline‐2,5(6 HH )‐diones

摘要

> 6‐Butyl‐3‐((dimethylamino)methylene)pyrano[3,2‐ c ]quinolinone and 6‐butyl pyrano[3,2‐ c ]quinolone‐3‐carbonitrile were efficiently synthesized in good yield. These two new precursors were used to obtain some novel heteroannulated pyrano[3,2‐ c ]quinolone derivatives from heterocyclization reactions with various binucleophiles. These heteroannulation reactions afforded novel heterocyclic systems fused to the pyranoquinolinone at face c , such as pyrazole, pyrimidine, pyridine, and pyrazolopyranone.