Fe ₃3 O ₄4 Magnetic Nanoparticles (MNPs) as Reusable Catalyst for the Synthesis of Chromene Derivatives Using Multicomponent Reaction of 4‐Hydroxycumarin Basis on Cheletropic Reaction

摘要

> A series of oxocyclopenta[c]chromenes were synthesized via three component reaction of 4‐hydroxycumarin, dialkyl acetylenedicarboxylate, α‐bromo ketones, and triphenylphosphine in the presence of catalytic amount of Fe ₃ O ₄ magnetic nanoparticles (MNPs) (15?mol%) under solvent‐free conditions at 70°C. Facile, green, easy separation of product and catalyst, and high yields of products are advantages of these reactions.