Solute carrier organic anion transporter family member 4A1 (SLCO4A1) as a prognosis marker of colorectal cancer

Ban Myung Jin; Ji Sang Hee; Lee Chi-Kyu; Bae Sang Byung; Kim Han Jo; Ahn Tae Sung; Lee Moon Soo; Baek Moo-Jun; Jeong Dongjun

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Solute carrier organic anion transporter family member 4A1 (SLCO4A1) as a prognosis marker of colorectal cancer

机译：溶质载体有机阴离子转运蛋白构件4a1（slco4a1）作为结直肠癌的预后标志物

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Purpose Solute carrier organic anion transporter family member 4A1 (SLCO4A1) is involved in the transport of various compounds, including sugars, bile salts, organic acids, metal ions, amine compounds, and estrogen. SLCO4A1 is highly expressed in several cancers and a gender bias has been observed in colorectal cancer (CRC). We investigated SLCO4A1 expression, its prognostic value in patients with CRC, and its role in CRC cell proliferation and metastasis.

机译：目的溶质载体有机阴离子转运蛋白构件4a1（slco4a1）涉及各种化合物的运输，包括糖，胆汁盐，有机酸，金属离子，胺化合物和雌激素。 SLCO4A1在几种癌症中高表达，结直肠癌（CRC）中已经观察到性别偏差。我们研究了SLCO4A1表达，其CRC患者的预后价值及其在CRC细胞增殖和转移中的作用。

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来源
《Journal of Cancer Research and Clinical Oncology》 |2017年第8期|共11页
作者
Ban Myung Jin; Ji Sang Hee; Lee Chi-Kyu; Bae Sang Byung; Kim Han Jo; Ahn Tae Sung; Lee Moon Soo; Baek Moo-Jun; Jeong Dongjun;
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作者单位

Soonchunhyang Univ Coll Med Dept Otorhinolaryngol Head &

Neck Surg Cheonan Chungcheongnam;

Soonchunhyang Univ Soonchunhyang Med Sci Res Inst Cheonan Chungcheongnam South Korea;

Soonchunhyang Univ Coll Med Dept Otorhinolaryngol Head &

Neck Surg Cheonan Chungcheongnam;

Soonchunhyang Univ Coll Med Dept Oncol Cheonan Chungcheongnam South Korea;

Soonchunhyang Univ Coll Med Dept Oncol Cheonan Chungcheongnam South Korea;

Soonchunhyang Univ Coll Med Dept Surg Cheonan Chungcheongnam South Korea;

Soonchunhyang Univ Coll Med Dept Surg Cheonan Chungcheongnam South Korea;

Soonchunhyang Univ Coll Med Dept Surg Cheonan Chungcheongnam South Korea;

Soonchunhyang Univ Soonchunhyang Med Sci Res Inst Cheonan Chungcheongnam South Korea;

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正文语种 eng
中图分类肿瘤学;
关键词
Colorectal cancer; Solute carrier organic anion transporter family member 4A1; Prognostic value; Cell proliferation; Metastasis;

机译：结直肠癌;溶质载体有机阴离子转运蛋白成员4a1;预后值;细胞增殖;转移;

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专利

1. Solute carrier organic anion transporter family member 4A1 (SLCO4A1) as a prognosis marker of colorectal cancer [J] . Ban Myung Jin, Ji Sang Hee, Lee Chi-Kyu, Journal of Cancer Research and Clinical Oncology . 2017,第8期

机译：溶质载体有机阴离子转运蛋白构件4a1（slco4a1）作为结直肠癌的预后标志物
2. Case of pachydermoperiostosis with solute carrier organic anion transporter family, member 2A1 (SLCO2A1) mutations [J] . Minakawa Satoko, Kaneko Takahide, Niizeki Hironori, The Journal of dermatology . 2015,第9期

机译：伴有溶质载体有机阴离子转运蛋白家族，成员2A1（SLCO2A1）突变的上皮性子宫内膜异位症
3. Lack of association between polymorphisms in the prostaglandin F(2α) receptor and solute carrier organic anion transporter family 2A1 genes and intraocular pressure response to prostaglandin analogs. [J] . Catherine A McCarty, Richard Berg, Richard Patchett, Ophthalmic genetics . 2012,第2期

机译：前列腺素F（2α）受体和溶质载体有机阴离子转运蛋白家族2A1基因的多态性与对前列腺素类似物的眼压响应之间缺乏关联。
4. The effects of transmembrane anion transporters compounds on cellular migration on human oral cancer cells [C] . IGLESIAS-HERNANDEZ P., RIVAS-ECHEVERRIA C. International Conference on Health Science and Biomedical Systems . 2014

机译：跨膜阴离子转运蛋白化合物对人口腔癌细胞细胞迁移的影响
5. Assessment of the drug-drug interaction potential of anionic components in the diet and herbal medicines on organic anion transporters (SLC22 family). [D] . Wang, Li. 2013

机译：评估饮食和草药中阴离子成分在有机阴离子转运蛋白（SLC22系列）上的药物-药物相互作用潜力。
6. Expression and regulation of prostaglandin transporters ATP-binding cassette subfamily C member 1 and 9 and solute carrier organic anion transporter family member 2A1 and 5A1 in the uterine endometrium during the estrous cycle and pregnancy in pigs [O] . Hwanhee Jang, Yohan Choi, Inkyu Yoo, 2017

机译：猪动情周期和妊娠期子宫内膜中前列腺素转运蛋白ATP结合盒C亚家族C成员1和9溶质载体有机阴离子转运蛋白家族2A1和5A1的表达和调控
7. Expression and regulation of prostaglandin transporters, ATP-binding cassette, subfamily C, member 1 and 9, and solute carrier organic anion transporter family, member 2A1 and 5A1 in the uterine endometrium during the estrous cycle and pregnancy in pigs [O] . Hwanhee Jang, Yohan Choi, Inkyu Yoo, 2017

机译：表达和调节前列腺素转运蛋白，aTp结合盒，亚家族C，成员1和9，溶质载体有机阴离子转运蛋白家族，成员2a1和5a1在子宫内膜发情周期和猪的怀孕期间

Solute carrier organic anion transporter family member 4A1 (SLCO4A1) as a prognosis marker of colorectal cancer

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