Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy

Kuo Hsiang-Wei; Liu Tung-Hsia; Tsou Hsiao-Hui; Hsu Ya-Ting; Wang Sheng-Chang; Fang Chiu-Ping; Liu Chia-Chen; Chen Andrew C. H.; Liu Yu-Li

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Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy

机译：炎症趋化因子eotaxin-1与海洛因依赖性患者在美沙酮维持治疗下的年龄相关

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Background Degeneration of central neurons and fibers has been observed in postmortem brains of heroin dependent patients. However, there are no biomarkers to predict the severity of neurodegeneration related to heroin dependence. A correlation has been reported between inflammatory C-C motif chemokine ligand 11 (CCL11, or eotaxin-1) and neurodegeneration in Alzheimer's disease.

机译：在海洛因依赖性患者的后期大脑中观察到中枢神经元和纤维的背景退化。然而，没有生物标志物预测与海洛因依赖性相关的神经变性的严重程度。在阿尔茨海默氏病中炎症C-C基序趋化因子11（CCL11或Eotaxin-1）和神经变性之间的相关性已经报道了相关性。

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来源
《Drug and alcohol dependence》 |2018年第2018期|共6页
作者
Kuo Hsiang-Wei; Liu Tung-Hsia; Tsou Hsiao-Hui; Hsu Ya-Ting; Wang Sheng-Chang; Fang Chiu-Ping; Liu Chia-Chen; Chen Andrew C. H.; Liu Yu-Li;
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作者单位

Natl Hlth Res Inst Ctr Neuropsychiat Res 35 Keyan Rd Zhunan 350 Miaoli County Taiwan;

Natl Hlth Res Inst Ctr Neuropsychiat Res 35 Keyan Rd Zhunan 350 Miaoli County Taiwan;

Natl Hlth Res Inst Inst Populat Hlth Sci Div Biostat &

Bioinformat Zhunan Miaoli County Taiwan;

Natl Hlth Res Inst Inst Populat Hlth Sci Div Biostat &

Bioinformat Zhunan Miaoli County Taiwan;

Natl Hlth Res Inst Ctr Neuropsychiat Res 35 Keyan Rd Zhunan 350 Miaoli County Taiwan;

Natl Hlth Res Inst Ctr Neuropsychiat Res 35 Keyan Rd Zhunan 350 Miaoli County Taiwan;

Natl Hlth Res Inst Ctr Neuropsychiat Res 35 Keyan Rd Zhunan 350 Miaoli County Taiwan;

Northwell Hlth Syst Zucker Hillside Hosp Dept Psychiat Glen Oaks NY USA;

Natl Hlth Res Inst Ctr Neuropsychiat Res 35 Keyan Rd Zhunan 350 Miaoli County Taiwan;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Amyloid beta; CCL11; FGF-2; Insomnia; Methadone;

机译：淀粉样蛋白β;ccl11;fgf-2;失眠;美沙酮;

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专利

1. Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy [J] . Kuo Hsiang-Wei, Liu Tung-Hsia, Tsou Hsiao-Hui, Drug and alcohol dependence . 2018,第期

机译：炎症趋化因子eotaxin-1与海洛因依赖性患者在美沙酮维持治疗下的年龄相关
2. Satisfaction With Methadone Among Heroin-Dependent Patients With Current Substance Use Disorders During Methadone Maintenance Treatment [J] . Perez de los Cobos Jose, Trujols Joan, Sinol Nuria, Journal of clinical psychopharmacology . 2016,第2期

机译：美沙酮维持治疗期间海洛因依赖者当前物质使用障碍患者对美沙酮的满意度
3. Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients [J] . Hsin-Chou Yang, Shih-Kai Chu, Chieh-Liang Huang, PLoS Genetics . 2016,第3期

机译：美沙酮维持治疗的全基因组药物基因组学研究鉴定了与美沙酮的血浆浓度相关的 CYP2B6 ， SPON1 和 GSG1L 的SNP rs17180299和多种单倍型海洛因依赖患者的italic> R-和 S-对映体
4. Electro-acupuncture (EA) as an adjunct therapy to methadone maintenance treatment (MMT) in heroin addiction: A study of 2D EEG power spectral topography and Morlet wavelet [C] . Shiman Farid, F. Molaei, Oladazimi Maysam, 2012 IEEE EMBS Conference on Biomedical Engineering and Sciences. . 2012

机译：电针（EA）作为海洛因成瘾中美沙酮维持治疗（MMT）的辅助疗法：二维EEG功率谱和Morlet小波的研究
5. The Comparison of Prescriptions Dispensed For Methadone Maintenance Patients to Non-Methadone Maintenance Patients for the Treatment of Chronic Diseases using PharmaNet Data [D] . Maruyama, Anna. 2012

机译：使用PharmaNet数据比较美沙酮维持治疗患者和非美沙酮维持治疗患者治疗慢性疾病的处方比较
6. Prevalence of pain and its socio-demographic and clinical correlates among heroin-dependent patients receiving methadone maintenance treatment [O] . Ying-Jia Yang, Yan-Min Xu, Wen-Cai Chen, -1

机译：美沙酮维持治疗中依赖海洛因的患者的疼痛发生率及其社会人口统计学和临床相关性
7. Prevalence of pain and its socio-demographic and clinical correlates among heroin-dependent patients receiving methadone maintenance treatment [O] . Ying-Jia Yang, Yan-Min Xu, Wen-Cai Chen, 2017

机译：海洛因依赖性患者接受美沙酮维持治疗的痛苦及其社会人口统计和临床关联的患病率

Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy

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