AJR Teaching File: Multiple Symmetric Abnormalities in a Radionuclide Bone Scan

摘要

A 41-year-old woman underwent clinical and imaging workup for metastatic medullary thyroid carcinoma. The TC methylene diphosphonate whole-body hone scintigraphy shows no evidence of osseous metastatic disease from medullary thyroid cancer. However, it shows multiple skeletal abnormalities: agenesis of the clavicles, frontal bone bossing, and hypoplastic iliac bones (Fig. 1A). A posteroanterior chest radiograph confirms the absence of clavicles (Fig. IB). Alateral CT of head and neck shows frontal bossing, wormian bones, and extensive dental works related to numerous dental abnormalities (Fig. 1C). An axial CT image of the base of the skull shows wormian bones (Fig. ID).