Twice daily short‐message‐based re‐education could improve        <i >Helicobacter pyloriHelicobacter pylori        eradication rate in young population: A prospective randomized controlled study

Wang Tongyu; Yang Xiaoxiao; Li Yueyue; Li Lixiang; Liu Jing; Ji Chaoran; Sun Yiyuan; Li Yanqing; Zuo Xiuli

摘要

Abstract <section numbered="no" xml:id="hel12569-sec-0001"> <title type="main">Background > To investigate the effects of twice daily short‐message‐based re‐education (SMRE) before taking medicine for Helicobacter pylori ( H?pylori ) eradication. </section> <section numbered="no" xml:id="hel12569-sec-0002"> <title type="main">Materials and Methods > Treatment‐naive patients with H?pylori infection were prescribed 14‐day quadruple regimen consisting of lansoprazole 30?mg, colloidal bismuth pectin 200?mg, amoxicillin 1000?mg, and clarithromycin 500?mg twice daily. Patients were randomly allocated to SMRE group or control group. Patients in control group received oral and written instructions at outpatient clinic. In contrast, patients in the SMRE group received extra short messages including dosage and time of administration twice daily. Successful H?pylori eradication was assessed using the 13 C‐urea breath test 6?weeks after treatment. The compliance, adverse events, and patient satisfaction were also analyzed. </section> <section numbered="no" xml:id="hel12569-sec-0003"> <title type="main">Results > A total of 310 patients were enrolled in the intention‐to‐treat (ITT) and 283 in the per‐protocol (PP) analysis. For young patients, the eradication rates were significantly higher in SMRE group than those in control group in PP analysis (88.6% vs 71.2%, P ?=?0.036), while for patients of all age groups, the eradication rate improvements were not statistically significant. The eradication rates in SMRE group and </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“main”XML：ID =“Hel12569-Abs-0001”XML：Lang =“en”> <标题类型=“main”>抽象</ title> <secto numbyed =“no”xml：id = “hel12569-sec-0001”> <标题类型=“main”>背景</ title> >在服药之前，调查两次每日短信的重新教育（SMRE）的影响幽门螺杆菌（ H？幽门螺杆）根除。 </ p> </ section> <部分编号=“否”XML：ID =“HEL12569-SEC-0002”> <标题类型=“MAIN”>材料和方法</标题> <P>治疗 - 天真患者 H？Pylori </ i>感染是由Lansoprazole 30〜Mg，胶体铋果胶200μmγ铋，Amoxicillin 1000〜20×mg，每天两次，每天两次。患者随机分配给SMRE组或对照组。对照组患者在门诊诊所接受口头和书面指示。相比之下，SMRE组中的患者收到额外的短消息，包括每日两次给药时的剂量和时间。使用 13 / sop> c-urea呼气试验6？治疗后评估成功的 h？幽门螺杆菌。还分析了合规性，不良事件和患者的满意度。 </ p> </ section> <部分编号=“否”XML：ID =“HEL12569-SEC-0003”> <标题类型=“MAIN”>结果</标题> <P>共注册了310名患者310名患者在每协定（PP）分析中的意图（ITT）和283中。对于年轻患者，SMRE组的根除率显着高于PP分析中的对照组（88.6％vs 71.2％， P </ i>？= 0.036），而对于所有年龄组的患者，根除率改善没有统计学意义。 SMRE组的根除率 </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-32409/'>《Helicobacter》</a> <b style="margin: 0 2px;">|</b><span>2019年第3期</span><b style="margin: 0 2px;">|</b><span>共6页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wang Tongyu&option=202" target="_blank" rel="nofollow">Wang Tongyu;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yang Xiaoxiao&option=202" target="_blank" rel="nofollow">Yang Xiaoxiao;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Yueyue&option=202" target="_blank" rel="nofollow">Li Yueyue;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Lixiang&option=202" target="_blank" rel="nofollow">Li Lixiang;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Liu Jing&option=202" target="_blank" rel="nofollow">Liu Jing;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ji Chaoran&option=202" target="_blank" rel="nofollow">Ji Chaoran;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sun Yiyuan&option=202" target="_blank" rel="nofollow">Sun Yiyuan;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Yanqing&option=202" target="_blank" rel="nofollow">Li Yanqing;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Zuo Xiuli&option=202" target="_blank" rel="nofollow">Zuo Xiuli;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of GastroenterologyQilu Hospital of Shandong UniversityJinan Shandong China;</p> <p>Department of GastroenterologyQilu Hospital of Shandong UniversityJinan Shandong China;</p> <p>Department of GastroenterologyQilu Hospital of Shandong UniversityJinan Shandong China;</p> <p>Department of GastroenterologyQilu Hospital of Shandong UniversityJinan Shandong China;</p> <p>Department of GastroenterologyQilu Hospital of Shandong UniversityJinan Shandong China;</p> <p>Department of GastroenterologyQilu Hospital of Shandong UniversityJinan Shandong China;</p> <p>Department of GastroenterologyQilu Hospital of Shandong UniversityJinan Shandong China;</p> <p>Department of GastroenterologyQilu Hospital of Shandong UniversityJinan Shandong China;</p> <p>Department of GastroenterologyQilu Hospital of Shandong UniversityJinan Shandong China;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/183.html" title="微生物学">微生物学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=compliance&option=203" rel="nofollow">compliance;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=eradication&option=203" rel="nofollow">eradication;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Helicobacter pylori&option=203" rel="nofollow">Helicobacter pylori;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=short‐message‐based re‐education&option=203" rel="nofollow">short‐message‐based re‐education;</a> </p> <div class="translation"> 机译：遵守;根除;幽门螺杆菌;基于短信的重新教育; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704025099045.html">Twice daily short‐message‐based re‐education could improve <i >Helicobacter pyloriHelicobacter pylori eradication rate in young population: A prospective randomized controlled study</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wang Tongyu&option=202" target="_blank" rel="nofollow" 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Arkkila P.</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=SepplK.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,SepplK.</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=FrkkilM.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,FrkkilM.</a> <span> <a href="/journal-cn-6057/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 世界核心医学期刊文摘：胃肠病学分册 </a> </span> <span> . 2006</span><span>,第11期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-1661_thesis/02022250418.html">中药清化汤根除幽门螺杆菌随机对照研究</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=吴兵&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 吴兵</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=陶琳&option=202" target="_blank" rel="nofollow" class="tuijian_auth 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<b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120100095100.html">过氧化氢在制备幽门螺杆菌感染根除治疗药物中的应用及制备的药物</a> <b>[P]</b> . <span> 中国专利： CN109223825A </span> <span> . 2019-01-18</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130452941089.html">Helicobacter pylori eradication determination method based on change rate of pepsinogen I / II ratio</a> <b>[P]</b> . <span> 外国专利：  JP2949474B2 </span> <span> . 1999-09-13</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：基于胃蛋白酶原I / II比变化率的幽门螺杆菌根除测定方法 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 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Twice daily short‐message‐based re‐education could improve Helicobacter pyloriHelicobacter pylori eradication rate in young population: A prospective randomized controlled study

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