Detection of Malignancy Among Suspicious Thyroid Nodules < 1 cm on Ultrasound with Various Thyroid Image Reporting and Data Systems

摘要

Background: In patients undergoing active surveillance of papillary thyroid microcarcinoma, definitive therapyusually preceded by a definitive diagnostic procedureis not recommended until evidence of disease progression is obtained, as stated in the American Thyroid Association guidelines. This is because the deferring of definitive diagnosis and therapy until disease progression has no impact on the disease-specific survival. This study evaluated the malignancy rate and probability of thyroid nodules, which was further stratified based on the size cutoff value of 1cm, with suspicious findings on ultrasonography (US), by using various malignant stratification systems.