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Fabrication of polylactic acid/halloysite nanotube scaffolds by foam injection molding for tissue engineering

机译：用泡沫注塑成型组织工程制备聚乳酸/霍罗伊岩纳米管支架

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Abstract >This study presents the improvement of mechanical properties and cell viability of polylactic acid/halloysite nanotube (PLA/HNT) scaffolds that were fabricated by foam injection molding. In this regard, firstly PLA and HNT were compounded on a twin screw extruder by melt mixing method within the HNT loadings of 1, 3, 5 wt%. Then, neat PLA and PLA/HNT pellets were foam injected molded to obtain tensile test samples. The mechanical properties of the scaffolds were determined by tensile test and methyl‐thiazol‐tetrazolium technique was used for determination of cell viability. The results have shown that the scaffold with 3 wt% of HNT addition gave the highest mechanical strength among the fabricated scaffolds with 124.2% and 79.2% of increments in tensile strength and elongation, respectively. Also, 3 wt% of HNT demonstrated the highest cell viability among the obtained scaffolds due to its improved scaffold morphology. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“Main”XML：Lang =“en”> <标题类型=“main”>抽象</ title> 本研究提高了通过泡沫注射成型制造的聚乳酸/霍罗伊岩纳米管（PLA / HNT）支架的机械性能和细胞活力的改善。在这方面，首先通过熔融混合方法在1,3,5wt％的HNT载荷内通过熔融混合方法将PLA和HNT混合在双螺杆挤出机上。然后，整洁的PLA和PLA / HNT颗粒是注入模塑的泡沫以获得拉伸试验样品。支架的力学性能通过拉伸试验和甲基 - 噻唑 - 四唑鎓技术测定用于测定细胞活力。结果表明，具有3wt％的HNT加入的支架在制造的支架中产生了最高的机械强度，分别为抗拉强度和伸长率为124.2％和79.2％的增量。此外，由于其改进的支架形态，3wt％的HNT在所获得的支架中显示出最高的细胞活力。</ p> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-29566/'>《Polymer Composites》</a> <b style="margin: 0 2px;">|</b><span>2020年第2期</span><b style="margin: 0 2px;">|</b><span>共11页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/7852.html" title="增强塑料、填充塑料">增强塑料、填充塑料;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=cell viability&option=203" rel="nofollow">cell viability;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=foam injection molding&option=203" rel="nofollow">foam injection molding;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=halloysite nanotube&option=203" rel="nofollow">halloysite nanotube;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=mechanical strength&option=203" rel="nofollow">mechanical strength;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=polylactide&option=203" rel="nofollow">polylactide;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=scaffold&option=203" rel="nofollow">scaffold;</a> </p> <div class="translation"> 机译：细胞活力;泡沫注射成型;霍罗伊石纳米管;机械强度;聚丙烯酯;脚手架; 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