Comparison of 55 degrees Wide-Field Spectral Domain Optical Coherence Tomography and Conventional 30 degrees Optical Coherence Tomography for the Assessment of Diabetic Macular Edema

摘要

Purpose: To compare conventional 30 degrees spectral domain optical coherence tomography (SD-OCT) with 55 degrees wide-field SD-OCT for the assessment of diabetic macular edema (DME). Methods: This study included 50 DME patients. Both 55 degrees and 30 degrees SD-OCT was conducted. Two readers evaluated scans according to a standardized grading protocol. Intergrader agreement as well as agreement between 30 degrees and 55 degrees SD-OCT were assessed. Results: Intergrader agreement (.) was strong and ranged from 0.79 to 1.0. Perfect interdevice agreement (kappa = 1.0) was found for the detection of intra-and subretinal fluid. Excellent agreement (kappa >= 0.9) was found for the presence of epiretinal membrane (kappa = 0.92) and cotton-wool spots (kappa = 0.92). A strong agreement was found for the presence of hard exudates (kappa = 0.89) and microaneurysms (kappa = 0.81). A moderate correlation was found for ellipsoid zone integrity (kappa = 0.69) and configuration of the vitreomacular interface (VMI) (kappa = 0.69). A weak agreement was found for retinal pigment epithelium atrophy (kappa = 0.51) and external limiting membrane integrity (kappa = 0.35). Conclusion: Wide- field OCT imaging may be beneficial for evaluating DME, particularly for assessing the VMI and the integrity of hyperreflective bands. (C) 2017 S. Karger AG, Basel