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首页> 外文期刊>Russian journal of physical chemistry, B. >Nuclear Magnetic Ions of Magnesium, Calcium, and Zinc as a Powerful and Universal Means for Killing Cancer Cells
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Nuclear Magnetic Ions of Magnesium, Calcium, and Zinc as a Powerful and Universal Means for Killing Cancer Cells

机译:镁,钙和锌的核磁离子是杀死癌细胞的强大和通用手段

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摘要

Magnetic isotope effect controls enzymatic DNA synthesis and strongly, by 2-3 times, suppresses catalytic activity of polymerases and increases even more strongly, by 20-50 times, the mortality of cancer cells. Catalyzing ions Mg-25(2+), Ca-43(2+), and Zn-67(2+) carrying magnetic nuclei are shown to efficiently kill cancer cells. The advantage of these ions for practical medicine is that being injected in blood they are captured selectively and almost exclusively by cancer cells inducing their death. The healthy cells capture these ions much less efficiently (perhaps due to the lower penetrability of their membranes) and are not vulnerable to these ions in comparison with cancer cells. Of course, penetrability of cells is identical for magnetic and nonmagnetic ions, but only the former kill cancer cells.
机译:磁性同位素效应控制酶DNA合成,强烈地,抑制聚合酶的催化活性,甚至更强烈地增加20-50次,癌细胞的死亡率。 催化离子Mg-25(2+),Ca-43(2+)和XN-67(2+)携带磁性核被证明有效杀死癌细胞。 这些离子的实际药物的优点是在血液中注射它们被选择性地,并且几乎完全被诱导其死亡的癌细胞捕获。 健康的细胞捕获这些离子的效率远低(也许是由于它们的膜的渗透性较低),并且与癌细胞相比,这些离子不易受影响。 当然,细胞的渗透性对于磁性和非磁性离子是相同的,但只有前者杀死癌细胞。

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