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Microencapsulated duck oil diacylglycerol: Preparation and application as anti-obesity agent

机译:微胶囊化鸭油二酰基甘油:制备和应用作为抗肥胖剂

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摘要

Although duck oil diacylglycerol (DAG) is considered a beneficial food additive, its production, stability and functions are not sufficiently analyzed. In the present study, the alkaline hydrolysis - lipase esterification method was utilized to obtain high purity 1,3-DAG, and the production rate surpassed 94%. In addition, DAG micro encapsulation using sodium caseinate and beta-cyclodextrin was optimized and characterized. The micro encapsulated duck DAG (mdDAG) was smooth in surface and cubic in shape, with particle size narrowly distributed between 10 pm and 100 pm with high dispersion. The peroxide values and mass loss values illustrated the evidently inhibitory effects of mdDAG on the oxidation process. Moreover, the effects of mdDAG intake on hyperlipidemic Wistar rats were evaluated systematically via anthropometrical and serum biochemical parameters, organ indexes and histological analysis of the liver. Results indicated that mdDAG intake was safe and acted as a functional ingredient to reduce the body weight, stimulate the lipid metabolism in viscera, and lessen obesity.
机译:虽然鸭油二酰基甘油(DAG)被认为是一种有益的食品添加剂,但其生产,稳定性和功能不充分分析。在本研究中,利用碱性水解 - 脂肪酶酯化方法获得高纯度1,3-DAG,生产速率超过94%。此外,使用酪蛋白酸钠和β-环糊精的DAG微包膜进行了优化和表征。微包封的鸭子DAG(MDDAG)在表面和立方体的表面上光滑,粒径狭窄地分布在10μm和100μm具有高分散体之间。过氧化物值和质量损失值说明了MDDAG对氧化过程的显着抑制作用。此外,系统通过人体测量和血清生物化学参数,器官指数和肝脏组织学分析系统地评估了MDDAG摄入对高脂质血症Wistar大鼠的影响。结果表明,MDDAG摄入是安全的,充当官能成分,以降低体重,刺激内脏的脂质代谢,并减少肥胖症。

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