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The stability and gastro-intestinal digestion of curcumin emulsion stabilized with soybean oil bodies

机译:用大豆油体稳定姜黄素乳液的稳定性和胃肠消化

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摘要

The study aimed at stabilizing the curcumin emulsions (CEs) using the soybean seed oil bodies (SSOBs) and investigated the gastrointestinal digestion of the CEs. The particle size decreased (P < 0.05) with the increasing concentration of SSOBs from 1.0 wt% to 5.0 wt%. The CEs stabilized with the SSOBs exhibited excellent stability at pH 2.0 and 6.0-10.0. The CEs were stable against the aggregation at 100-500 mmol/L NaCl concentration and elevated temperature. The droplet size analysis and confocal laser scanning microscope observation results indicated that the fat droplets aggregated in the CEs under the gastric conditions at 30 min and afterward it gradually dispersed. Under the simulated intestinal condition, the droplet size of the CEs significantly decreased compared to the simulated gastric conditions (P < 0.05). The release rate of curcumin continuously increased during 180 min digestion under the intestinal conditions. Therefore, SSOBs could be used as the natural emulsifiers and novel carriers in delivering the lipophilic bioactive compounds.
机译:研究旨在使用大豆种子油体(SSOB)稳定姜黄素乳液(CES),并研究CES的胃肠道消化。粒度降低(P <0.05),其浓度的浓度从1.0wt%升至5.0wt%。用SSOB稳定的CE在pH 2.0和6.0-10.0下表现出优异的稳定性。 CES在100-500mmol / L NaCl浓度下稳定稳定,浓度为100-500mmol / L NaCl浓度和升高的温度。液滴尺寸分析和共聚焦激光扫描显微镜观察结果表明,在胃条件下在30分钟内汇聚在CES下的脂肪液滴,然后逐渐分散。在模拟肠道条件下,与模拟胃条件相比,CE的液滴尺寸显着降低(P <0.05)。在肠道条件下180分钟消化期间,姜黄素的释放速率在180分钟内持续增加。因此,SSOB可以用作递送亲脂性生物活性化合物的天然乳化剂和新型载体。

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