Lanostane-type Triterpenoids from Ganoderma lucidum and G. multipileum Fruiting Bodies

Pham Thanh Binh; Nguyen Phuong Thao; Nguyen Thi Luyen; Duong Thu Trang; Phung Thi Xuan Binh; Nguyen Phuong Dai Nguyen; Nguyen Tuan Hiep; Nguyen Hai Dang; Tran Manh Tri; Nguyen Tien Dat

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Lanostane-type Triterpenoids from Ganoderma lucidum and G. multipileum Fruiting Bodies

机译：来自Ganoderma lucidum和G.多偏果实的Lanostane型三萜类化合物

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Sixteen lanostane-type triterpeneoids were isolated from the fruiting bodies of wild Ganoderma lucidum and G. multipileum. The new structures 3S,24S,25,26-tetrahydroxy-5a-lanost-8-en-11-one (1) and ganodermanondiol 24,25-acetonide (10) were elucidated by means of spectroscopic data and Mosher's experiments. Lanosta-7,9(11)-dien-3 beta-ol (9) strongly inhibited alpha-glucosidase with the IC50 values of 198.8 mu M in compared with acarbose (IC50 712.4 mu M).

机译：从野生灵芝和G.多相的结果体中分离出六个Lanosostane型三萜甾丙烯骨。通过光谱数据和Mosher的实验，阐明了新的结构3s，24s，25,26-四羟基-11-1-14-14-14-11-14-14,25-丙酮（10）。 Lanosta-7,9（11）-dien-3β-Ol（9）与氨基糖（IC50 712.4 mu m）相比，强烈抑制α-葡糖苷酶198.8μm的IC50值。

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来源
《Natural product communications》 |2018年第11期|共4页
作者
Pham Thanh Binh; Nguyen Phuong Thao; Nguyen Thi Luyen; Duong Thu Trang; Phung Thi Xuan Binh; Nguyen Phuong Dai Nguyen; Nguyen Tuan Hiep; Nguyen Hai Dang; Tran Manh Tri; Nguyen Tien Dat;
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作者单位

VAST Inst Marine Biochem 18 Hoang Quoc Viet Hanoi Vietnam;

VAST Inst Marine Biochem 18 Hoang Quoc Viet Hanoi Vietnam;

VAST Ctr Res &

Technol Transfer 18 Hoang Quoc Viet Hanoi Vietnam;

VAST Inst Marine Biochem 18 Hoang Quoc Viet Hanoi Vietnam;

Dien Luc Univ 235 Hoang Quoc Viet Hanoi Vietnam;

Univ Tay Nguyen Dept Biol 567 Le Duan Dac Lac City Vietnam;

Natl Inst Med Mat 3B Quang Trung Hanoi Vietnam;

VAST Inst Marine Biochem 18 Hoang Quoc Viet Hanoi Vietnam;

Vietnam Natl Univ VNU Univ Sci Fac Chem 19 Le Thanh Tong Hanoi Vietnam;

VAST Ctr Res &

Technol Transfer 18 Hoang Quoc Viet Hanoi Vietnam;

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原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词
Ganoderma lucidum; Ganoderma multipileum; Ganodermataceae; Lanostane; alpha-Glucosidase;

机译：Ganoderma lucidum;Ganoderma multipleile;ganodermataceae;lanoderane;α-葡糖苷酶;

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2. Potential of biocontrol agents against Ganoderma lucidum causing basal stem rot in mesquite ( Prosopis cineraria ) in arid regions of India [J] . Ritu Mawar, Deepesh Sharma, Ladhu Ram 林业研究（英文版） . 2021,第003期
3. Magnetic Ganoderma Lucidum Spores(mGLS):A Novel Regulatable Targeted Drug Delivery System [J] . Bin Han, Guixia Liu, Zuobin Wang, 仿生工程学报（英文版） . 2021,第004期
4. Lanostane-type Triterpenoids from Ganoderma lucidum and G. multipileum Fruiting Bodies [J] . Pham Thanh Binh, Nguyen Phuong Thao, Nguyen Thi Luyen, Natural product communications . 2018,第11期

机译：来自Ganoderma lucidum和G.多偏果实的Lanostane型三萜类化合物
5. A new lanostane-type triterpene from the fruiting bodies of Ganoderma lucidum. [J] . Luo J, Zhao YY, Li ZB Journal of Asian natural products research . 2002,第2期

机译：来自灵芝子实体的一种新的羊毛甾烷型三萜。
6. Ganoderma multipileum, the correct name for 'G. lucidum' in tropical Asia [J] . Wang Dong-Mei, Wu Sheng-Hua, Su Ching-Hua, Botanical Studies . 2009,第4期

机译：灵芝，'G。的正确名称。透明”在热带亚洲
7. Influence of culture substrate on the phytochemical contents of fruiting bodies and spores of 3 varieties of Ganoderma lucidum [C] . Zuofa ZHANG, Weiming CAI, Guoying LV, International Conference on Energy and Environmental Protection . 2018

机译：培养基对3种Ganoderma lucidum的果实植物植物和孢子植物的影响
8. Comparative studies on the biological activities of selected Chinese medicinal fungi: Ganoderma species and Cordyceps species. An exploration of whether the different parts of their fruiting bodies bear different properties. [D] . Yue, Gar Lee Grace. 2006

机译：某些中药真菌：灵芝和冬虫夏草的生物活性比较研究。探索其子实体的不同部分是否具有不同的属性。
9. Cytotoxic lanostane-type triterpenoids from the fruiting bodies of Ganoderma lucidum and their structure–activity relationships [O] . Shaodan Chen, Xiangmin Li, Tianqiao Yong, 2017

机译：灵芝子实体的细胞毒性羊毛甾烷型三萜及其结构-活性关系
10. Enhanced production of polysaccharides and triterpenoids in Ganoderma lucidum fruit bodies on induction with signal transduction during the fruiting stage [O] . Liyun Ye, Shengrong Liu, Fan Xie, 2018

机译：在果实期间通过信号转导的诱导诱导果实的多糖和三萜类化合物的生产

Lanostane-type Triterpenoids from Ganoderma lucidum and G. multipileum Fruiting Bodies

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