Effects of combined treatment of tadalafil and tamsulosin on bladder dysfunction via the inhibition of afferent nerve activities in a rat model of bladder outlet obstruction

Furuta Akira; Suzuki Yasuyuki; Igarashi Taro; Koike Yusuke; Egawa Shin; Yoshimura Naoki

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Effects of combined treatment of tadalafil and tamsulosin on bladder dysfunction via the inhibition of afferent nerve activities in a rat model of bladder outlet obstruction

机译：达拉夫林和茶香蛋白在膀胱出口梗阻大鼠模型中抑制膀胱功能障碍对膀胱功能障碍的影响

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摘要

To investigate the effects of combined treatment of tadalafil (a phosphodiesterase-5 inhibitor) and tamsulosin (an alpha(1)-adrenoceptor antagonist) on bladder dysfunction in a rat model of bladder outlet obstruction (BOO).

机译：探讨达拉非（磷虾 - 5抑制剂）和祖菊酯（Alpha（1） - 一种抑制剂拮抗剂）对膀胱出口梗阻（BOO）大鼠膀胱功能障碍的影响的影响。

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来源
《International Urology and Nephrology》 |2018年第5期|共6页
作者
Furuta Akira; Suzuki Yasuyuki; Igarashi Taro; Koike Yusuke; Egawa Shin; Yoshimura Naoki;
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作者单位

Jikei Univ Dept Urol Sch Med Minato Ku 3-25-8 Nishi Shinbashi Tokyo 1058461 Japan;

Tokyo Metropolitan Rehabil Hosp Dept Urol Sumida Ku 2-14-1 Tsutsumitouri Tokyo 1310034 Japan;

Jikei Univ Dept Urol Sch Med Minato Ku 3-25-8 Nishi Shinbashi Tokyo 1058461 Japan;

Jikei Univ Dept Urol Sch Med Minato Ku 3-25-8 Nishi Shinbashi Tokyo 1058461 Japan;

Jikei Univ Dept Urol Sch Med Minato Ku 3-25-8 Nishi Shinbashi Tokyo 1058461 Japan;

Univ Pittsburgh Dept Urol Sch Med Suite 700 Kaufmann Med Bldg 3471 Fifth Ave Pittsburgh PA;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词
Bladder outlet obstruction; Combination therapy; Rats; Tadalafil; Tamsulosin;

机译：膀胱出口梗阻;联合疗法;大鼠;达拉非;蛋白素;

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专利

1. Effects of combined treatment of tadalafil and tamsulosin on bladder dysfunction via the inhibition of afferent nerve activities in a rat model of bladder outlet obstruction [J] . Furuta Akira, Suzuki Yasuyuki, Igarashi Taro, International Urology and Nephrology . 2018,第5期

机译：达拉夫林和茶香蛋白在膀胱出口梗阻大鼠模型中抑制膀胱功能障碍对膀胱功能障碍的影响
2. Inhibitory effects of silodosin on the bladder mechanosensitive afferent activities and their relation with bladder myogenic contractions in male rats with bladder outlet obstruction [J] . Aizawa Naoki, Watanabe Daiji, Fukuhara Hiroshi, Neurourology and urodynamics. . 2018,第6期

机译：粘土机对膀胱机械敏感性活动的抑制作用及膀胱出口阻塞雄性大鼠膀胱肌遗传学中的关系及其关系
3. Effects of the phosphodiesterase 5 inhibitor Tadalafil on bladder function in a rat model of partial bladder outlet obstruction [J] . Kawai Yuko, Oka Michiko, Yoshinaga Ryohei, Neurourology and urodynamics. . 2016,第4期

机译：磷酸二酯酶5抑制剂他达拉非对部分膀胱出口梗阻大鼠模型膀胱功能的影响
4. A basic urine flowmeter and a non-invasive bladder pressure measurement device used in conjunction for the diagnosis of bladder outlet obstruction [C] . Caffarel J., Drinnan M.J., Pickard R.S., 5th IET Seminar on Appropriate Healthcare Technologies for Developing Countries . 2008

机译：基本尿液流量计和非侵入性膀胱压力测量装置一起用于诊断膀胱出口梗阻
5. A case-control study exploring the relationships between risk factors of detrusor underactivity and bladder outlet obstruction and incomplete bladder emptying in community-dwelling women aged 65 or older who have overactive bladder symptoms [D] . Park, Jeongok. 2011

机译：病例对照研究探讨了逼尿肌活动不足和膀胱出口梗阻的危险因素与膀胱过度活跃症的65岁以上社区居民妇女膀胱排空不完全之间的关系
6. Effects of Spinal and Peripheral Injection of α1A or α1D Adrenoceptor Antagonists on Bladder Activity in Rat Models with or without Bladder Outlet Obstruction [O] . Jae Heon Kim, Ji Sung Shim, Seung Chul Kang, 2011

机译：脊髓和周围注射α1A或α1D肾上腺素受体拮抗剂对有或无膀胱出口梗阻模型大鼠膀胱活动的影响
7. Effects of chronic administration of tamsulosin and tadalafil, alone or in combination, in rats with bladder outlet obstruction induced by chronic nitric oxide deficiency [O] . Rommel Prata Regadas, Ricardo Reges, João Batista Gadelha Cerqueira, 2014

机译：坦索罗辛和他达拉非单独或联合用药对慢性一氧化氮缺乏所致膀胱出口梗阻大鼠的影响

Effects of combined treatment of tadalafil and tamsulosin on bladder dysfunction via the inhibition of afferent nerve activities in a rat model of bladder outlet obstruction

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