Clinical outcomes of alpelisib in hormone receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer by next-generation sequencing-detected PIK3CA alteration status and phosphatase and tensin homolog loss: Biomarker analysis from the SOLAR-1 study

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Clinical outcomes of alpelisib in hormone receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer by next-generation sequencing-detected PIK3CA alteration status and phosphatase and tensin homolog loss: Biomarker analysis from the SOLAR-1 study

机译：通过下一代测序检测的PIK3CA改变状态和磷酸酶和磷酸酶和磷酸酶及磷酸酶及磷酸酶和磷酸酶的临床蛋白酶阳性，人体表皮生长因子受体-2阴性晚期乳腺癌的临床结果：生物标志物分析太阳能-1研究

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《Intelligence: A Multidisciplinary Journal》 |2020年第2020期|共5页
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1. Clinical outcomes of alpelisib in hormone receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer by next-generation sequencing-detected PIK3CA alteration status and phosphatase and tensin homolog loss: Biomarker analysis from the SOLAR-1 study [J] . Intelligence: A Multidisciplinary Journal . 2020,第期

机译：通过下一代测序检测的PIK3CA改变状态和磷酸酶和磷酸酶和磷酸酶及磷酸酶及磷酸酶和磷酸酶的临床蛋白酶阳性，人体表皮生长因子受体-2阴性晚期乳腺癌的临床结果：生物标志物分析太阳能-1研究
2. Loss of phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers. [J] . Dave B, Migliaccio I, Gutierrez MC, Journal of Clinical Oncology . 2011,第2期

机译：在人类表皮生长因子受体2过表达的局部晚期乳腺癌中，磷酸酶和张力蛋白同源物或磷酸肌醇3激酶活化的丧失以及对曲妥珠单抗或拉帕替尼的应答。
3. RIBOCICLIB (RIB) plus LETROZOLE (LET) IN OLDER PATIENTS (PTS) WITH HORMONE RECEPTOR-POSITIVE (HR plus ), HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR-2-NEGATIVE (HER2-) ADVANCED BREAST CANCER (ABC): SUBGROUP RESULTS FROM THE PHASE 3B COMPLEEMENT-1 TRIAL [J] . De Laurentiis Michelino, Campone Mario, Alba Conejo Emilio, The Breast : . 2019,第Suppla2期

机译：Ribociclib（肋骨）加仑唑（Let）在老年患者（PTS）中，具有激素受体阳性（HR加），人表皮生长因子受体-2阴性（HER2-）晚期乳腺癌（ABC）：亚组结果来自阶段 3B Complement-1试验
4. PIK3CA mutations phosphatase and tensin homolog human epidermal growth factor receptor 2 and insulin-like growth factor 1 receptor and adjuvant tamoxifen resistance in postmenopausal breast cancer patients [O] . Karin Beelen, Mark Opdam, Tesa M Severson, 2014

机译：绝经后乳腺癌患者的PIK3CA突变磷酸酶和张力蛋白同源物人表皮生长因子受体2和胰岛素样生长因子1受体及他莫昔芬辅助耐药
5. 163P Population-adjusted comparison of SOLAR-1 and BOLERO-2: PFS with second-line alpelisib + fulvestrant vs everolimus + exemestane in postmenopausal pts with PIK3CA-mut hormone-receptor positive (HR+) human epidermal growth factor receptor-2 negative (HER2-) advanced breast cancer (ABC) [O] . E.M. Ciruelos, T. Delea, A. Moynahan, 2020

机译：163P人口调整的太阳能-1和Bolero-2的比较：PFS与二线alpelisib +富勒斯特语+ Everolimus + Extemestane在绝经后PTS，PIK3CA-MUT激素受体阳性（HR +）人体表皮生长因子受体-2阴性（HER2 - ）晚期乳腺癌（ABC）

Clinical outcomes of alpelisib in hormone receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer by next-generation sequencing-detected PIK3CA alteration status and phosphatase and tensin homolog loss: Biomarker analysis from the SOLAR-1 study

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