SEARCH FOR ANTIMICROBIAL AGENTS: QUINOXALINE AS A PROMISING TARGET

摘要

A set of ten new 2,3-diphenyl-6-sulfonamido quinoxaline derivatives was synthesized and screened for antimicrobial activity by disk diffusion method. Test derivatives R3, R5, R"1 and R"2 show promising results against bacterial strains S. aureus gram positive and E. coli gram negative organism with the concentration 1000 mug/mL in disk diffusion method. Rest of the derivatives show sensitivity against the same organisms. All the synthesized derivatives were confirmed by their spectral data.