Systemic inhibition of IL-6/Stat3 signalling protects against experimental osteoarthritis

Latourte Augustin; Cherifi Chahrazad; Maillet Jeremy; Ea Hang-Korng; Bouaziz Wafa; Funck-Brentano Thomas; Cohen-Solal Martine; Hay Eric; Richette Pascal

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Systemic inhibition of IL-6/Stat3 signalling protects against experimental osteoarthritis

机译：系统抑制IL-6 / Stat3信号传导可保护实验性骨关节炎

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Objective To investigate the impact of systemic inhibition of interleukin 6 (IL-6) or signal transducer and activator of transcription (Stat3) in an experimental model of osteoarthritis (OA)

机译：目的探讨白细胞介素6（IL-6）或信号传感器及转录激活剂（STAT3）的系统抑制作用在骨关节炎的实验模型中的影响（OA）

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来源
《Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research》 |2017年第4期|共8页
作者
Latourte Augustin; Cherifi Chahrazad; Maillet Jeremy; Ea Hang-Korng; Bouaziz Wafa; Funck-Brentano Thomas; Cohen-Solal Martine; Hay Eric; Richette Pascal;
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作者单位

Hop Lariboisiere INSERM U1132 Paris France;

Hop Lariboisiere INSERM U1132 Paris France;

Hop Lariboisiere INSERM U1132 Paris France;

Hop Lariboisiere INSERM U1132 Paris France;

Hop Lariboisiere INSERM U1132 Paris France;

Hop Lariboisiere INSERM U1132 Paris France;

Hop Lariboisiere INSERM U1132 Paris France;

Hop Lariboisiere INSERM U1132 Paris France;

Hop Lariboisiere INSERM U1132 Paris France;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
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1. Systemic inhibition of IL-6/Stat3 signalling protects against experimental osteoarthritis [J] . Latourte Augustin, Cherifi Chahrazad, Maillet Jeremy, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2017,第4期

机译：系统抑制IL-6 / Stat3信号传导可保护实验性骨关节炎
2. IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings [J] . Huynh Nhu Mai, Chung Yoon Hee, Shin Eun-Joo, Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research . 2018,第期

机译：IL-6敲除小鼠免受可卡因诱导的点燃行为; JAK2 / Stat3和PACAP信号的可能参与
3. Proline protects liver from D-galactosamine hepatitis by activating the IL-6/STAT3 survival signaling pathway [J] . Yoko Obayashi, Harumi Arisaka, Shintaro Yoshida Amino acids . 2012,第6期

机译：脯氨酸通过激活IL-6 / STAT3生存信号通路保护肝脏免受D-半乳糖胺肝炎的侵害
4. Cryptotanshinone Potentiates the Apoptotic Effects of Doxorubicin via inhibition of STAT3 activity in Gastric Cancer [C] . Jia Jia, Yangfan Guo, Pei Liu, International conference of molecular simulations and applied informatics technologies . 2012

机译：隐丹参酮通过抑制胃癌中STAT3的活性增强阿霉素的凋亡作用。
5. Immunoprotective role of an IL-6/gp130/STAT3 signaling axis controlling lymphocyte trafficking during fever. [D] . Vardam, Trupti D. 2011

机译：IL-6 / gp130 / STAT3信号轴控制发烧期间淋巴细胞运输的免疫保护作用。
6. GMI ablates cancer stemness and cisplatin resistance in oral carcinomas stem cells through IL-6/Stat3 signaling inhibition [O] . Tung Yuan Wang, Cheng-Chia Yu, Pei-Ling Hsieh, 2017

机译：GMI通过IL-6 / Stat3信号抑制作用消除口腔癌干细胞的癌干性和顺铂耐药性
7. IL-6/STAT3 signalling blockade protects against experimental osteoarthritis in mice [O] . A. Latourte, J. Maillet, C. Cherifi, 2016

机译：IL-6 / Stat3信号障碍物保护小鼠的实验性骨关节炎

Systemic inhibition of IL-6/Stat3 signalling protects against experimental osteoarthritis

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