Mutant Huntingtin accumulation in the nucleus affects nucleolar function in Huntington's disease mouse models and patients at early stages

Soenmez A.; Spieth S.; Mustafa R.; Kojer K.; Litke C.; Kochi J.; Orth M.; Liss B.; Parlato R.

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Mutant Huntingtin accumulation in the nucleus affects nucleolar function in Huntington's disease mouse models and patients at early stages

机译：核心亨廷顿核中的核心积累影响亨廷顿氏病小鼠模型和早期阶段的核心功能

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来源
《Acta physiologica》 |2019年第s719期|共1页
作者
Soenmez A.; Spieth S.; Mustafa R.; Kojer K.; Litke C.; Kochi J.; Orth M.; Liss B.; Parlato R.;
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作者单位

Ulm Univ Inst Appl Physiol Ulm Germany;

Ulm Univ Inst Appl Physiol Ulm Germany;

Ulm Univ Inst Appl Physiol Ulm Germany;

Ulm Univ Dept Neurol Ulm Germany;

Heidelberg Univ Inst Anat &

Cell Biol Heidelberg Germany;

Ulm Univ Inst Appl Physiol Ulm Germany;

Ulm Univ Dept Neurol Ulm Germany;

Ulm Univ Inst Appl Physiol Ulm Germany;

Ulm Univ Inst Appl Physiol Ulm Germany;

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正文语种 eng
中图分类人体生理学;
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1. Mutant Huntingtin accumulation in the nucleus affects nucleolar function in Huntington's disease mouse models and patients at early stages [J] . Soenmez A., Spieth S., Mustafa R., Acta physiologica . 2019,第S719期

机译：核心亨廷顿核中的核心积累影响亨廷顿氏病小鼠模型和早期阶段的核心功能
2. Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease [J] . Chuan-En Wang1 Suzanne Tydlacka1 Adam L. Orr1 Shang-Hsun Yang2 Rona K. Graham3 Michael R. Hayden3 Shihua Li1 Anthony W.S. Chan12 and Xiao-Jiang Li1 Human Molecular Genetics . 2008,第17期

机译：小鼠和猴子模型中N端突变型亨廷顿蛋白的积累与亨廷顿舞蹈病的发病机制有关
3. Mutant huntingtin reduction in astrocytes slows disease progression in the BACHD conditional Huntington's disease mouse model [J] . Wood Tara E., Barry Joshua, Yang Zhenquin, Human Molecular Genetics . 2019,第3期

机译：突变体亨廷顿减少星形胶质细胞减缓了疾病的疾病小鼠模型中的疾病进展
4. An Integrative Proteomic Approach to Identify Huntingtin Protein Networks Using a Novel BAC Transgenic Model of Huntington's Disease [C] . Dyna Shirasaki, Erin R. Greiner, Pinmanee Boontheung, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：一种综合的蛋白质组学方法，用于使用亨廷顿氏病的新型BAC转基因模型鉴定亨廷蛋白网络
5. Therapeutic implications of mutant huntingtin-induced dysregulation of brain iron homeostasis in a mouse model of Huntington's disease. [D] . Marks, Eileen S. 2011

机译：亨廷顿氏病小鼠模型中突变亨廷顿蛋白诱导的脑铁稳态失调的治疗意义。
6. Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntingtons disease [O] . Chuan-En Wang, Suzanne Tydlacka, Adam L. Orr, -1

机译：小鼠和猴子模型中N端突变型亨廷顿蛋白的积累与亨廷顿舞蹈病的发病机制有关
7. Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease [O] . Wang, Chuan-En, Tydlacka, Suzanne, Orr, Adam L., 2008

机译：小鼠和猴子模型中N端突变型亨廷顿蛋白的积累与亨廷顿舞蹈病的发病机制有关

Mutant Huntingtin accumulation in the nucleus affects nucleolar function in Huntington's disease mouse models and patients at early stages

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