Reducing sample size requirements for future ALS clinical trials with a dedicated electrical impedance myography system

Shefner Jeremy M.; Rutkove Seward B.; Caress James B.; Benatar Michael; David William S.; Cartwright Michael S.; Macklin Eric A.; Bohorquez Jose L.

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Reducing sample size requirements for future ALS clinical trials with a dedicated electrical impedance myography system

机译：减少未来ALS临床试验的样本大小要求，具有专用的电气阻抗Myography系统

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Objective: In this longitudinal multicenter cohort study, we evaluated the potential of a dedicated electrical impedance myography (EIM) device to assess ALS progression and the system's basic reproducibility and diagnostic accuracy.

机译：目的：在这种纵向多中心队列研究中，我们评估了专用电阻抗幻图（EIM）设备的潜力，以评估ALS进展和系统的基本再现性和诊断准确性。

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来源
《Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration》 |2018年第8期|共7页
作者
Shefner Jeremy M.; Rutkove Seward B.; Caress James B.; Benatar Michael; David William S.; Cartwright Michael S.; Macklin Eric A.; Bohorquez Jose L.;
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作者单位

Barrow Neurol Inst Dept Neurol Phoenix AZ 85013 USA;

Beth Israel Deaconess Med Ctr Dept Neurol Boston MA 02215 USA;

Wake Forest Sch Med Dept Neurol Winston Salem NC USA;

Univ Miami Dept Neurol Miami FL USA;

Harvard Med Sch Boston MA USA;

Wake Forest Sch Med Dept Neurol Winston Salem NC USA;

Harvard Med Sch Boston MA USA;

Myolex Inc San Francisco CA USA;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Electrical impedance myography; biomarker; clinical trials; ALS;

机译：电阻抗幻图;生物标志物;临床试验;als;

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专利

1. Reducing sample size requirements for future ALS clinical trials with a dedicated electrical impedance myography system [J] . Shefner Jeremy M., Rutkove Seward B., Caress James B., Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration . 2018,第7a8期

机译：减少未来ALS临床试验的样本大小要求，具有专用的电气阻抗Myography系统
2. Electrical impedance myography goes global: collaborative efforts to advance a promising preclinical and clinical tool for the development of future DMD therapies [J] . van Putten M., Mantuano P., Aartsma-Rus A., Neuromuscular disorders: NMD . 2019,第Suppla1期

机译：电阻幻想幻图出现了全球性：协作努力推进一个有前途的临床前和临床工具，以发展未来的DMD疗法
3. Cross-sectional evaluation of electrical impedance myography and quantitative ultrasound for the assessment of duchenne muscular dystrophy in a clinical trial setting [J] . RutkoveS.B., GeisbushT.R., MijailovicA., Pediatric neurology . 2014,第1期

机译：电阻抗肌成像和定量超声的横断面评估，用于在临床试验中评估杜兴肌营养不良
4. Machine Learning classification of MRI features of Alzheimer's disease and mild cognitive impairment subjects to reduce the sample size in clinical trials [C] . Escudero Javier, Zajicek John P., Ifeachor Emmanuel 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2011

机译：针对阿尔茨海默氏病和轻度认知障碍受试者的MRI特征的机器学习分类，以减少临床试验中的样本量
5. Electrical Impedance Myography and Quantitative Ultrasound as Biomarkers in Duchenne Muscular Dystrophy. [D] . Shklyar, Irina. 2014

机译：电阻抗肌电图和定量超声作为Duchenne肌营养不良症的生物标志物。
6. Electrical impedance myography for reducing sample size in Duchenne muscular dystrophy trials [O] . Melanie L. Leitner, Kush Kapur, Basil T. Darras, 2020

机译：电阻抗肌成像在杜氏肌营养不良症试验中减少样本量
7. Electrical impedance myography for reducing sample size in Duchenne muscular dystrophy trials [O] . Melanie L. Leitner, Kush Kapur, Basil T. Darras, 2019

机译：用于减少Duchenne肌营养不良试验中的样品大小的电阻肌图

Reducing sample size requirements for future ALS clinical trials with a dedicated electrical impedance myography system

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